Temporal Trends in Gestational Diabetes Prevalence, Treatment, and Outcomes at Aarhus University Hospital, Skejby, between 2004 and 2016

Per Glud Ovesen, Jens Fuglsang, Mette Bisgaard Andersen, Charlotte Wolff, Olav Bjørn Petersen, H David McIntyre

Abstract

Background: The prevalence of gestational diabetes (GDM) is increasing worldwide. The most important risk of GDM in pregnancy is excessive fetal growth, increasing the risk of complications during delivery as well as long-term complications like obesity and diabetes in both the mother and the offspring.

Method: All women with GDM who delivered a singleton between 2004 and 2016 were included. The treatment of GDM patients sought to achieve normal blood glucose levels, primarily by diet and exercise. If the glycemic targets were not reached, insulin therapy was initiated. Birth weight and birth weight Z-score was calculated corrected for gender and gestational age at delivery.

Results: The study included 1910 women. The number of GDM women increased significantly each year over the course of the study, as did the proportion requiring insulin therapy. Birth weight and birth weight Z-score fell significantly over the years largely due to a decrease in large for gestational age frequency from 29% to around 19%.

Conclusion: During the last 13 years, the number of women diagnosed with GDM has increased. Furthermore, the proportion of GDM women receiving insulin treatment has increased. The birth weight in diet-treated women has been virtually normal for the last 5 years of the reported period.

Original languageEnglish
JournalJournal of Diabetes Research
Volume2018
Pages (from-to)5937059
ISSN2314-6745
DOIs
Publication statusPublished - 2018
Externally publishedYes

Keywords

  • Adult
  • Birth Weight
  • Blood Glucose
  • Denmark/epidemiology
  • Diabetes, Gestational/blood
  • Diet
  • Exercise
  • Female
  • Hospitals, University
  • Humans
  • Hypoglycemic Agents/therapeutic use
  • Insulin/therapeutic use
  • Pregnancy
  • Prevalence
  • Treatment Outcome

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