Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study

Lasse Hjort Jakobsen; Anne Stidsholt Roug; Andreas Kiesbye Øvlisen; Claus Werenberg Marcher; Hans Beier Ommen; Kim Theilgaard-Mönch; Peter Møller; Claudia Schöllkopf; Daniel Kristensen; Therese Maria Henriette Naur; Martin Bøgsted; Tarec Christoffer El-Galaly; Marianne Tang Severinsen

doi:10.1111/bjh.17213

Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study

Lasse Hjort Jakobsen, Anne Stidsholt Roug, Andreas Kiesbye Øvlisen, Claus Werenberg Marcher, Hans Beier Ommen, Kim Theilgaard-Mönch, Peter Møller, Claudia Schöllkopf, Daniel Kristensen, Therese Maria Henriette Naur, Martin Bøgsted, Tarec Christoffer El-Galaly, Marianne Tang Severinsen

24 Citations (Scopus)

Abstract

In the present study, we quantify the progress in overall survival (OS) during the period 2000-2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22% in 2002 to 31% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10% among patients aged 50-75 years and a small absolute increase in those aged >75 years.

Original language	English
Journal	British Journal of Haematology
Volume	193
Issue number	3
Pages (from-to)	482-487
Number of pages	6
ISSN	0007-1048
DOIs	https://doi.org/10.1111/bjh.17213
Publication status	Published - May 2021

Keywords

acute myeloid leukaemia
temporal survival
real&#8208
world patients
real-world patients

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10.1111/bjh.17213

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Hjort Jakobsen, L., Roug, A. S., Kiesbye Øvlisen, A., Werenberg Marcher, C., Beier Ommen, H., Theilgaard-Mönch, K., Møller, P., Schöllkopf, C., Kristensen, D., Maria Henriette Naur, T., Bøgsted, M., Christoffer El-Galaly, T., & Tang Severinsen, M. (2021). Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study. British Journal of Haematology, 193(3), 482-487. https://doi.org/10.1111/bjh.17213

Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study. / Hjort Jakobsen, Lasse; Roug, Anne Stidsholt; Kiesbye Øvlisen, Andreas et al.
In: British Journal of Haematology, Vol. 193, No. 3, 05.2021, p. 482-487.

Research output: Contribution to journal › Journal article › Research › peer-review

Hjort Jakobsen, L, Roug, AS, Kiesbye Øvlisen, A, Werenberg Marcher, C, Beier Ommen, H, Theilgaard-Mönch, K, Møller, P, Schöllkopf, C, Kristensen, D, Maria Henriette Naur, T, Bøgsted, M, Christoffer El-Galaly, T & Tang Severinsen, M 2021, 'Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study', British Journal of Haematology, vol. 193, no. 3, pp. 482-487. https://doi.org/10.1111/bjh.17213

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title = "Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study",

abstract = "In the present study, we quantify the progress in overall survival (OS) during the period 2000-2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22\% in 2002 to 31\% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10\% among patients aged 50-75 years and a small absolute increase in those aged >75 years.",

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doi = "10.1111/bjh.17213",

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AU - Kiesbye Øvlisen, Andreas

AU - Werenberg Marcher, Claus

AU - Beier Ommen, Hans

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AU - Maria Henriette Naur, Therese

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AU - Christoffer El-Galaly, Tarec

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AB - In the present study, we quantify the progress in overall survival (OS) during the period 2000-2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22% in 2002 to 31% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10% among patients aged 50-75 years and a small absolute increase in those aged >75 years.

KW - acute myeloid leukaemia

KW - temporal survival

KW - real&#8208

KW - world patients

KW - real-world patients

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Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study

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