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The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

Telemetric continuous glucose monitoring during the COVID-19 pandemic in isolated hospitalized patients in Denmark - a randomized controlled exploratory trial

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OBJECTIVE: To investigate whether telemetric continuous glucose monitoring (CGM) in hospitalized and isolated patients with diabetes mellitus and coronavirus disease 2019 (COVID-19) is associated with better glycaemic control and fewer patient-health care worker contacts compared to blood glucose monitoring by traditional point-of-care (POC) glucose testing and to investigate the user aspect of implementing a CGM-system in-hospital.

METHODS: A randomized controlled exploratory trial was performed on hospitalized and isolated patients with diabetes and COVID-19 from May 2020 until February 2021 at Nordsjællands Hospital, Denmark. Participants were randomized to nonblinded telemetric CGM (as the only glucose monitoring meth-od) or traditional POC glucose testing + blinded CGM. The primary endpoint was Time In Range (TIR) based on CGM data in both groups. A questionnaire about the user aspect of the CGM system was answered by health care personnel (HCP).

RESULTS: We included 64 participants in the analysis, 31 in the CGM group and 33 in the POC glucose group. TIR median was 46% for the CGM group and 68% for the POC glucose group (p=0.368). The mean glucose value for the CGM group was 11.1 mmol/L and 10.8 mmol/L in the POC glucose group (p=0.372). CGM was associated with fewer POC glucose measurements (p<0.001). Out of 30 HCPs, 28 preferred telemetric CGM over POC glucose testing.

CONCLUSION: Remote glucose monitoring by CGM did not improve glycaemic outcomes compared to traditional POC glucose testing but was associated with fewer patient-personnel contacts, saving time for HCPs performing diabetes-related tasks. Most HCPs preferred CGM.

Original languageEnglish
JournalDiabetes Technology & Therapeutics
ISSN1520-9156
DOIs
Publication statusE-pub ahead of print - 15 Sep 2021

ID: 67614936