Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

Palle B Jeppesen; Marek Pertkiewicz; Bernard Messing; Kishore Iyer; Douglas L Seidner; Stephen J D O'keefe; Alastair Forbes; Hartmut Heinze; Bo Joelsson

doi:10.1053/j.gastro.2012.09.007

Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

Palle B Jeppesen, Marek Pertkiewicz, Bernard Messing, Kishore Iyer, Douglas L Seidner, Stephen J D O'keefe, Alastair Forbes, Hartmut Heinze, Bo Joelsson

456 Citations (Scopus)

Abstract

Teduglutide, a glucagon-like peptide 2 analogue, might restore intestinal structural and functional integrity by promoting growth of the mucosa and reducing gastric emptying and secretion. These factors could increase fluid and nutrient absorption in patients with short bowel syndrome with intestinal failure (SBS-IF). We performed a prospective study to determine whether teduglutide reduces parenteral support in patients with SBS-IF.

Original language	English
Journal	Gastroenterology
Volume	143
Issue number	6
Pages (from-to)	1473-1481.e3
Number of pages	9
ISSN	0016-5085
DOIs	https://doi.org/10.1053/j.gastro.2012.09.007
Publication status	Published - 2012

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10.1053/j.gastro.2012.09.007

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abstract = "Teduglutide, a glucagon-like peptide 2 analogue, might restore intestinal structural and functional integrity by promoting growth of the mucosa and reducing gastric emptying and secretion. These factors could increase fluid and nutrient absorption in patients with short bowel syndrome with intestinal failure (SBS-IF). We performed a prospective study to determine whether teduglutide reduces parenteral support in patients with SBS-IF.",

author = "Jeppesen, \{Palle B\} and Marek Pertkiewicz and Bernard Messing and Kishore Iyer and Seidner, \{Douglas L\} and O'keefe, \{Stephen J D\} and Alastair Forbes and Hartmut Heinze and Bo Joelsson",

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T1 - Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

AU - Jeppesen, Palle B

AU - Pertkiewicz, Marek

AU - Messing, Bernard

AU - Iyer, Kishore

AU - Seidner, Douglas L

AU - O'keefe, Stephen J D

AU - Forbes, Alastair

AU - Heinze, Hartmut

AU - Joelsson, Bo

PY - 2012

Y1 - 2012

N2 - Teduglutide, a glucagon-like peptide 2 analogue, might restore intestinal structural and functional integrity by promoting growth of the mucosa and reducing gastric emptying and secretion. These factors could increase fluid and nutrient absorption in patients with short bowel syndrome with intestinal failure (SBS-IF). We performed a prospective study to determine whether teduglutide reduces parenteral support in patients with SBS-IF.

AB - Teduglutide, a glucagon-like peptide 2 analogue, might restore intestinal structural and functional integrity by promoting growth of the mucosa and reducing gastric emptying and secretion. These factors could increase fluid and nutrient absorption in patients with short bowel syndrome with intestinal failure (SBS-IF). We performed a prospective study to determine whether teduglutide reduces parenteral support in patients with SBS-IF.

UR - https://www.scopus.com/pages/publications/84869881880

U2 - 10.1053/j.gastro.2012.09.007

DO - 10.1053/j.gastro.2012.09.007

M3 - Journal article

C2 - 22982184

SN - 0016-5085

VL - 143

SP - 1473-1481.e3

JO - Gastroenterology

JF - Gastroenterology

IS - 6

ER -

Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

Abstract

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