T-cell dysfunction in HIV-1-infected patients with impaired recovery of CD4 cells despite suppression of viral replication

Christian Erikstrup; Gitte Kronborg; Nicolai Lohse; Sisse Rye Ostrowski; Jan Gerstoft; Henrik Ullum

doi:10.1097/QAI.0b013e3181ca3f7c

T-cell dysfunction in HIV-1-infected patients with impaired recovery of CD4 cells despite suppression of viral replication

Christian Erikstrup, Gitte Kronborg, Nicolai Lohse, Sisse Rye Ostrowski, Jan Gerstoft, Henrik Ullum

36 Citations (Scopus)

Abstract

CD4 T-cell recovery is impeded in some HIVinfected patients despite successful combination antiretroviral therapy (cART) with suppressed HIV RNA. We hypothesized that T-cell dysfunction would be increased in these patients.

Original language	English
Journal	J A I D S
Volume	53
Issue number	3
Pages (from-to)	303-10
Number of pages	8
ISSN	1525-4135
DOIs	https://doi.org/10.1097/QAI.0b013e3181ca3f7c
Publication status	Published - 1 Mar 2010

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title = "T-cell dysfunction in HIV-1-infected patients with impaired recovery of CD4 cells despite suppression of viral replication",

abstract = "CD4 T-cell recovery is impeded in some HIVinfected patients despite successful combination antiretroviral therapy (cART) with suppressed HIV RNA. We hypothesized that T-cell dysfunction would be increased in these patients.",

author = "Christian Erikstrup and Gitte Kronborg and Nicolai Lohse and Ostrowski, \{Sisse Rye\} and Jan Gerstoft and Henrik Ullum",

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AU - Erikstrup, Christian

AU - Kronborg, Gitte

AU - Lohse, Nicolai

AU - Ostrowski, Sisse Rye

AU - Gerstoft, Jan

AU - Ullum, Henrik

PY - 2010/3/1

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N2 - CD4 T-cell recovery is impeded in some HIVinfected patients despite successful combination antiretroviral therapy (cART) with suppressed HIV RNA. We hypothesized that T-cell dysfunction would be increased in these patients.

AB - CD4 T-cell recovery is impeded in some HIVinfected patients despite successful combination antiretroviral therapy (cART) with suppressed HIV RNA. We hypothesized that T-cell dysfunction would be increased in these patients.

UR - https://www.scopus.com/pages/publications/77649222712

U2 - 10.1097/QAI.0b013e3181ca3f7c

DO - 10.1097/QAI.0b013e3181ca3f7c

M3 - Journal article

C2 - 20048679

SN - 1525-4135

VL - 53

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EP - 310

JO - J A I D S

JF - J A I D S

IS - 3

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T-cell dysfunction in HIV-1-infected patients with impaired recovery of CD4 cells despite suppression of viral replication

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