Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

Rikke Krabek; Thomas Bergholt; Marianne Johansen; Lone Nikoline Nørgaard; Christian Heiring; Morten Hanefeld Dziegiel; Charlotte Kvist Ekelund

Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

Translated title of the contribution: Severe foetal anaemia caused by undetected alloimmunisation in a RhD-positive pregnant woman

Rikke Krabek, Thomas Bergholt, Marianne Johansen, Lone Nikoline Nørgaard, Christian Heiring, Morten Hanefeld Dziegiel, Charlotte Kvist Ekelund

Abstract

The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.

Translated title of the contribution	Severe foetal anaemia caused by undetected alloimmunisation in a RhD-positive pregnant woman
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	183
Issue number	32
Pages (from-to)	V02210124
ISSN	0041-5782
Publication status	Published - 9 Aug 2021

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https://ugeskriftet.dk/videnskab/svaer-fotal-anaemi-pa-grund-af-uerkendt-alloimmunisering-hos-rhd-positiv-gravid-kvinde

Cite this

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title = "Sv{\ae}r f{\o}tal an{\ae}mi p{\aa} grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde",

abstract = "The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.",

keywords = "Anemia, Hemolytic, Autoimmune, Erythroblastosis, Fetal/etiology, Female, Fetus, Humans, Infant, Newborn, Isoantibodies, Pregnancy, Pregnant Women",

author = "Rikke Krabek and Thomas Bergholt and Marianne Johansen and N{\o}rgaard, \{Lone Nikoline\} and Christian Heiring and Dziegiel, \{Morten Hanefeld\} and Ekelund, \{Charlotte Kvist\}",

year = "2021",

month = aug,

day = "9",

language = "Dansk",

volume = "183",

pages = "V02210124",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske L{\ae}geforening",

number = "32",

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TY - JOUR

T1 - Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

AU - Krabek, Rikke

AU - Bergholt, Thomas

AU - Johansen, Marianne

AU - Nørgaard, Lone Nikoline

AU - Heiring, Christian

AU - Dziegiel, Morten Hanefeld

AU - Ekelund, Charlotte Kvist

PY - 2021/8/9

Y1 - 2021/8/9

N2 - The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.

AB - The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.

KW - Anemia, Hemolytic, Autoimmune

KW - Erythroblastosis, Fetal/etiology

KW - Female

KW - Fetus

KW - Humans

KW - Infant, Newborn

KW - Isoantibodies

KW - Pregnancy

KW - Pregnant Women

UR - https://www.scopus.com/pages/publications/85113895053

M3 - Tidsskriftartikel

C2 - 34378528

SN - 0041-5782

VL - 183

SP - V02210124

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 32

ER -

Svær føtal anæmi på grund af uerkendt alloimmunisering hos RhD-positiv gravid kvinde

Abstract

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