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Susceptibility of Clostridium difficile toward antimicrobial agents used as feed additives for food animals

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@article{92e50e7cd72d4dfba23de39f2c4977ad,
title = "Susceptibility of Clostridium difficile toward antimicrobial agents used as feed additives for food animals",
abstract = "A total of 65 toxigenic Clostridium difficile strains isolated from patients with antibiotic-associated diarrhea were tested for susceptibility to avilamycin, flavomycin, monensin, and salinomycin. Except for flavomycin the substances showed in vitro efficacy comparable to reports of the currently most commonly used drugs for treatment of C. difficile. This indicates that these old compounds may be useful for the treatment of C. difficile infections in man and perhaps for other bacterial causes of diarrhea.",
keywords = "Animal Feed, Animals, Anti-Bacterial Agents, Clostridium difficile, Diarrhea, Drug Resistance, Bacterial, Enterocolitis, Pseudomembranous, Feces, Food Additives, Humans, Microbial Sensitivity Tests",
author = "Aarestrup, {Frank M{\o}ller} and Michael Tvede",
note = "{\textcopyright} Mary Ann Liebert, Inc.",
year = "2011",
month = mar,
day = "1",
doi = "10.1089/mdr.2010.0068",
language = "English",
volume = "17",
pages = "125--7",
journal = "Microbial Drug Resistance",
issn = "1076-6294",
publisher = "Mary Ann/Liebert, Inc. Publishers",
number = "1",

}

RIS

TY - JOUR

T1 - Susceptibility of Clostridium difficile toward antimicrobial agents used as feed additives for food animals

AU - Aarestrup, Frank Møller

AU - Tvede, Michael

N1 - © Mary Ann Liebert, Inc.

PY - 2011/3/1

Y1 - 2011/3/1

N2 - A total of 65 toxigenic Clostridium difficile strains isolated from patients with antibiotic-associated diarrhea were tested for susceptibility to avilamycin, flavomycin, monensin, and salinomycin. Except for flavomycin the substances showed in vitro efficacy comparable to reports of the currently most commonly used drugs for treatment of C. difficile. This indicates that these old compounds may be useful for the treatment of C. difficile infections in man and perhaps for other bacterial causes of diarrhea.

AB - A total of 65 toxigenic Clostridium difficile strains isolated from patients with antibiotic-associated diarrhea were tested for susceptibility to avilamycin, flavomycin, monensin, and salinomycin. Except for flavomycin the substances showed in vitro efficacy comparable to reports of the currently most commonly used drugs for treatment of C. difficile. This indicates that these old compounds may be useful for the treatment of C. difficile infections in man and perhaps for other bacterial causes of diarrhea.

KW - Animal Feed

KW - Animals

KW - Anti-Bacterial Agents

KW - Clostridium difficile

KW - Diarrhea

KW - Drug Resistance, Bacterial

KW - Enterocolitis, Pseudomembranous

KW - Feces

KW - Food Additives

KW - Humans

KW - Microbial Sensitivity Tests

U2 - 10.1089/mdr.2010.0068

DO - 10.1089/mdr.2010.0068

M3 - Journal article

C2 - 20950192

VL - 17

SP - 125

EP - 127

JO - Microbial Drug Resistance

JF - Microbial Drug Resistance

SN - 1076-6294

IS - 1

ER -

ID: 32665644