Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Surgically Induced Contrast Enhancements on Intraoperative and Early Postoperative MRI Following High-Grade Glioma Surgery: A Systematic Review

Research output: Contribution to journalReviewResearchpeer-review

  1. Treatment Response Biomarkers in Asthma and COPD

    Research output: Contribution to journalReviewResearchpeer-review

  2. Effect of Liraglutide on Vascular Inflammation Evaluated by [64Cu]DOTATATE

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Optimal Insertion Depth for Nasal Mid-Turbinate and Nasopharyngeal Swabs

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Infrared Thermography as a Method of Verification in Raynaud's Phenomenon

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Four-Dimensional Flow MRI of Abdominal Veins: A Systematic Review

    Research output: Contribution to journalReviewResearchpeer-review

View graph of relations

For the radiological assessment of resection of high-grade gliomas, a 72-h diagnostic window is recommended to limit surgically induced contrast enhancements. However, such enhancements may occur earlier than 72 h post-surgery. This systematic review aimed to assess the evidence on the timing of the postsurgical MRI. PubMed, Embase, Web of Science and Cochrane were searched following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only original research articles describing surgically induced contrast enhancements on MRI after resection for high-grade gliomas were included and analysed. The frequency of different contrast enhancement patterns on intraoperative MRI (iMRI) and early postoperative MRI (epMRI) was recorded. The search resulted in 1443 studies after removing duplicates, and a total of 12 studies were chosen for final review. Surgically induced contrast enhancements were reported at all time points after surgery, including on iMRI, but their type and frequency vary. Thin linear contrast enhancements were commonly found to be surgically induced and were less frequently recorded on postoperative days 1 and 2. This suggests that the optimal time to scan may be at or before this time. However, the evidence is limited, and higher-quality studies using larger and consecutively sampled populations are needed.

Original languageEnglish
Article number1344
JournalDiagnostics
Volume11
Issue number8
ISSN2075-4418
DOIs
Publication statusPublished - Aug 2021

    Research areas

  • Early postoperative MRI, High-grade glioma, Intraoperative MRI, Postoperative enhancement, Time window

ID: 67394142