Surgical radioguidance with beta-emitting radionuclides; challenges and possibilities: A position paper by the EANM

Pedro Fragoso Costa*, Kuangyu Shi, Soren Holm, Sergi Vidal-Sicart, Tereza Kracmerova, Giovanni Tosi, Jan Grimm, Dimitris Visvikis, Wolfram H Knapp, Gopinath Gnanasegaran, Fijs W B van Leeuwen

*Corresponding author for this work
3 Citations (Scopus)

Abstract

Radioguidance that makes use of β-emitting radionuclides is gaining in popularity and could have potential to strengthen the range of existing radioguidance techniques. While there is a strong tendency to develop new PET radiotracers, due to favorable imaging characteristics and the success of theranostics research, there are practical challenges that need to be overcome when considering use of β-emitters for surgical radioguidance. In this position paper, the EANM identifies the possibilities and challenges that relate to the successful implementation of β-emitters in surgical guidance, covering aspects related to instrumentation, radiation protection, and modes of implementation.

Original languageEnglish
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume51
Issue number10
Pages (from-to)2903-2921
Number of pages19
ISSN1619-7070
DOIs
Publication statusPublished - Aug 2024

Keywords

  • Beta emitting Radionuclides
  • Image guided surgery
  • Radiation exposure
  • Radioguidance
  • Radiotracers
  • Radioisotopes/chemistry
  • Surgery, Computer-Assisted/methods
  • Beta Particles/therapeutic use
  • Humans
  • Radiation Protection/methods
  • Nuclear Medicine
  • Radiopharmaceuticals

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