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Superior Orbital Fissure Syndrome and Ophthalmoplegia Caused by Varicella Zoster Virus with No Skin Eruption in a Patient Treated with Tumor Necrosis Alpha Inhibitor

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@article{eb44dde4b1374d51acbf939dd411022e,
title = "Superior Orbital Fissure Syndrome and Ophthalmoplegia Caused by Varicella Zoster Virus with No Skin Eruption in a Patient Treated with Tumor Necrosis Alpha Inhibitor",
abstract = "Varicella zoster virus lies dormant in the dorsal root ganglia after symptomatic chicken pox infection, usually in childhood. If the virus reactivates in the trigeminal ganglia, it can cause varicella zoster ophthalmicus, which can have severe ocular complications. We report a case of a 73-year-old woman in severe immunosuppression due to treatment with mycophenolate mofetil, glucocorticosteroids and a tumor necrosis factor alpha inhibitor. The reactivation caused superior orbital fissure syndrome, which has only rarely been described in relation to varicella zoster virus reactivation. In our case, the syndrome was seen along with severe encephalitis.",
author = "Helene Jensen and Thomsen, {Sidsel Thorup} and Hansen, {Stine Scott} and Munksgaard, {Signe Bruun} and Mette Lindelof",
year = "2015",
doi = "10.1159/000441325",
language = "English",
volume = "7",
pages = "221--6",
journal = "Case Reports in Neurology",
issn = "1662-680X",
publisher = "S.Karger AG",
number = "3",

}

RIS

TY - JOUR

T1 - Superior Orbital Fissure Syndrome and Ophthalmoplegia Caused by Varicella Zoster Virus with No Skin Eruption in a Patient Treated with Tumor Necrosis Alpha Inhibitor

AU - Jensen, Helene

AU - Thomsen, Sidsel Thorup

AU - Hansen, Stine Scott

AU - Munksgaard, Signe Bruun

AU - Lindelof, Mette

PY - 2015

Y1 - 2015

N2 - Varicella zoster virus lies dormant in the dorsal root ganglia after symptomatic chicken pox infection, usually in childhood. If the virus reactivates in the trigeminal ganglia, it can cause varicella zoster ophthalmicus, which can have severe ocular complications. We report a case of a 73-year-old woman in severe immunosuppression due to treatment with mycophenolate mofetil, glucocorticosteroids and a tumor necrosis factor alpha inhibitor. The reactivation caused superior orbital fissure syndrome, which has only rarely been described in relation to varicella zoster virus reactivation. In our case, the syndrome was seen along with severe encephalitis.

AB - Varicella zoster virus lies dormant in the dorsal root ganglia after symptomatic chicken pox infection, usually in childhood. If the virus reactivates in the trigeminal ganglia, it can cause varicella zoster ophthalmicus, which can have severe ocular complications. We report a case of a 73-year-old woman in severe immunosuppression due to treatment with mycophenolate mofetil, glucocorticosteroids and a tumor necrosis factor alpha inhibitor. The reactivation caused superior orbital fissure syndrome, which has only rarely been described in relation to varicella zoster virus reactivation. In our case, the syndrome was seen along with severe encephalitis.

U2 - 10.1159/000441325

DO - 10.1159/000441325

M3 - Journal article

VL - 7

SP - 221

EP - 226

JO - Case Reports in Neurology

JF - Case Reports in Neurology

SN - 1662-680X

IS - 3

ER -

ID: 46282981