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suPAR: The unspecific marker for disease presence, severity and prognosis

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  1. Azithromycin potentiates avian IgY effect against Pseudomonas aeruginosa in a murine pulmonary infection model

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  2. Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model

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  3. Hot topics on procalcitonin use in clinical practice, can it help antibiotic stewardship?

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  1. Linking Stressful Life Events and Chronic Inflammation Using suPAR (Soluble Urokinase Plasminogen Activator Receptor)

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  2. Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis

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  3. Circulating Osteopontin Levels and Outcomes in Patients Hospitalized for COVID-19

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Investigation of biomarkers that can promptly predict unfavourable outcome of critically illness is an emerging necessity taking into consideration the need for early intervention, the shortage of available beds in intensive care units and the considerable cost of hospitalisation. The most promising biomarker is soluble urokinase-type plasminogen activator receptor (suPAR). Three studies in large populations of critically ill patients and patients admitted to the emergency department have shown that concentrations >12ng/mL can safely predict unfavourable outcome. This review presents a thorough analysis of the data from these studies.

Original languageEnglish
JournalInternational Journal of Antimicrobial Agents
Volume41
Issue number1
Pages (from-to)s33-s34
ISSN0924-8579
DOIs
Publication statusPublished - Dec 2015

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