Sulfamethoxazol med trimethoprim som årsag til svær respirationsinsufficiens

Emilie Stokholm Bækgaard; Frederik Schwartz; Dennis B Holmgaard; Henrik Horwitz; David L Buck

doi:10.61409/V01250045

Sulfamethoxazol med trimethoprim som årsag til svær respirationsinsufficiens

Translated title of the contribution: Sulfamethoxazole with trimethoprim as a cause of severe respiratory failure

Emilie Stokholm Bækgaard^*, Frederik Schwartz, Dennis B Holmgaard, Henrik Horwitz, David L Buck

^*Corresponding author for this work

Abstract

In this case report, we describe a 49-year-old man who, after treatment with sulfamethoxazole and trimethoprim developed severe respiratory insufficiency, resulting in the need for veno-venous extracorporeal membrane oxygenation. As an infectious cause was initially suspected, he underwent extensive testing and imaging before this diagnosis was reached. After cessation of treatment with sulfamethoxazole and trimethoprim, he slowly recovered his respiratory function and was discharged after one month of mechanical ventilation.

Translated title of the contribution	Sulfamethoxazole with trimethoprim as a cause of severe respiratory failure
Original language	Danish
Article number	V01250045
Journal	Ugeskrift for Laeger
Volume	187
Issue number	45
Pages (from-to)	1-5
Number of pages	5
ISSN	0041-5782
DOIs	https://doi.org/10.61409/V01250045
Publication status	Published - 3 Nov 2025

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10.61409/V01250045Licence: CC BY-NC-ND

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title = "Sulfamethoxazol med trimethoprim som {\aa}rsag til sv{\ae}r respirationsinsufficiens",

abstract = "In this case report, we describe a 49-year-old man who, after treatment with sulfamethoxazole and trimethoprim developed severe respiratory insufficiency, resulting in the need for veno-venous extracorporeal membrane oxygenation. As an infectious cause was initially suspected, he underwent extensive testing and imaging before this diagnosis was reached. After cessation of treatment with sulfamethoxazole and trimethoprim, he slowly recovered his respiratory function and was discharged after one month of mechanical ventilation.",

keywords = "Humans, Male, Middle Aged, Respiratory Insufficiency/chemically induced, Trimethoprim, Sulfamethoxazole Drug Combination/adverse effects, Anti-Infective Agents/adverse effects, Anti-Bacterial Agents/adverse effects, Extracorporeal Membrane Oxygenation, Respiration, Artificial",

author = "B{\ae}kgaard, \{Emilie Stokholm\} and Frederik Schwartz and Holmgaard, \{Dennis B\} and Henrik Horwitz and Buck, \{David L\}",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2025",

month = nov,

day = "3",

doi = "10.61409/V01250045",

language = "Dansk",

volume = "187",

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T1 - Sulfamethoxazol med trimethoprim som årsag til svær respirationsinsufficiens

AU - Bækgaard, Emilie Stokholm

AU - Schwartz, Frederik

AU - Holmgaard, Dennis B

AU - Horwitz, Henrik

AU - Buck, David L

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2025/11/3

Y1 - 2025/11/3

N2 - In this case report, we describe a 49-year-old man who, after treatment with sulfamethoxazole and trimethoprim developed severe respiratory insufficiency, resulting in the need for veno-venous extracorporeal membrane oxygenation. As an infectious cause was initially suspected, he underwent extensive testing and imaging before this diagnosis was reached. After cessation of treatment with sulfamethoxazole and trimethoprim, he slowly recovered his respiratory function and was discharged after one month of mechanical ventilation.

AB - In this case report, we describe a 49-year-old man who, after treatment with sulfamethoxazole and trimethoprim developed severe respiratory insufficiency, resulting in the need for veno-venous extracorporeal membrane oxygenation. As an infectious cause was initially suspected, he underwent extensive testing and imaging before this diagnosis was reached. After cessation of treatment with sulfamethoxazole and trimethoprim, he slowly recovered his respiratory function and was discharged after one month of mechanical ventilation.

KW - Humans

KW - Male

KW - Middle Aged

KW - Respiratory Insufficiency/chemically induced

KW - Trimethoprim, Sulfamethoxazole Drug Combination/adverse effects

KW - Anti-Infective Agents/adverse effects

KW - Anti-Bacterial Agents/adverse effects

KW - Extracorporeal Membrane Oxygenation

KW - Respiration, Artificial

UR - https://www.scopus.com/pages/publications/105022522371

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DO - 10.61409/V01250045

M3 - Tidsskriftartikel

C2 - 41263174

SN - 0041-5782

VL - 187

SP - 1

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JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 45

M1 - V01250045

ER -

Sulfamethoxazol med trimethoprim som årsag til svær respirationsinsufficiens

Abstract

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