Successful pregnancy in a woman previously suffering from β-thalassemia following transplantation of ovarian tissue cryopreserved before puberty

Sara J Matthews; Helen Picton; Erik Ernst; Claus Y Andersen

doi:10.23736/S0026-4784.18.04240-5

Successful pregnancy in a woman previously suffering from β-thalassemia following transplantation of ovarian tissue cryopreserved before puberty

Sara J Matthews, Helen Picton, Erik Ernst, Claus Y Andersen

80 Citations (Scopus)

Abstract

Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman. Subsequently, she conceived following IVF treatment and delivered a healthy baby where the oocyte derived from the transplanted tissue. This is the first woman worldwide to have a baby where the ovarian tissue was frozen pre-pubertally and expand the therapeutic options for rare genetic diseases like thalassemia and girls who suffer from childhood cancer.

Original language	English
Journal	Minerva Ginecologica
Volume	70
Issue number	4
Pages (from-to)	432-435
Number of pages	4
ISSN	0026-4784
DOIs	https://doi.org/10.23736/S0026-4784.18.04240-5
Publication status	Published - Aug 2018
Externally published	Yes

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10.23736/S0026-4784.18.04240-5

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abstract = "Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman. Subsequently, she conceived following IVF treatment and delivered a healthy baby where the oocyte derived from the transplanted tissue. This is the first woman worldwide to have a baby where the ovarian tissue was frozen pre-pubertally and expand the therapeutic options for rare genetic diseases like thalassemia and girls who suffer from childhood cancer.",

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AU - Ernst, Erik

AU - Andersen, Claus Y

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AB - Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman. Subsequently, she conceived following IVF treatment and delivered a healthy baby where the oocyte derived from the transplanted tissue. This is the first woman worldwide to have a baby where the ovarian tissue was frozen pre-pubertally and expand the therapeutic options for rare genetic diseases like thalassemia and girls who suffer from childhood cancer.

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DO - 10.23736/S0026-4784.18.04240-5

M3 - Journal article

C2 - 29696941

VL - 70

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JO - Minerva Ginecologica

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ER -

Successful pregnancy in a woman previously suffering from β-thalassemia following transplantation of ovarian tissue cryopreserved before puberty

Abstract

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