Subtype-Specific Off-Label Treatment of Rosacea

Nita Wienholtz; Messoud Ashina; Jacob P Thyssen; Alexander Egeberg

doi:10.1159/000511984

Subtype-Specific Off-Label Treatment of Rosacea

Nita Wienholtz, Messoud Ashina, Jacob P Thyssen, Alexander Egeberg

4 Citations (Scopus)

Abstract

We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing treated with sumatriptan. The cases support previous notions that gastrointestinal comorbidities may be related to papulopustular lesions and that flushing may be related to neurogenic inflammation and migraine. The cases also imply that a new approach to rosacea management, based on endotypes and comorbidities, may be warranted.

Original language	English
Journal	Case Reports in Dermatology
Volume	13
Issue number	1
Pages (from-to)	121-128
Number of pages	8
ISSN	1662-6567
DOIs	https://doi.org/10.1159/000511984
Publication status	Published - 2021

Keywords

Flushing
Rifaximin
Rosacea
Sumatriptan

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10.1159/000511984

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title = "Subtype-Specific Off-Label Treatment of Rosacea",

abstract = "We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing treated with sumatriptan. The cases support previous notions that gastrointestinal comorbidities may be related to papulopustular lesions and that flushing may be related to neurogenic inflammation and migraine. The cases also imply that a new approach to rosacea management, based on endotypes and comorbidities, may be warranted.",

keywords = "Flushing, Rifaximin, Rosacea, Sumatriptan",

author = "Nita Wienholtz and Messoud Ashina and Thyssen, {Jacob P} and Alexander Egeberg",

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TY - JOUR

T1 - Subtype-Specific Off-Label Treatment of Rosacea

AU - Wienholtz, Nita

AU - Ashina, Messoud

AU - Thyssen, Jacob P

AU - Egeberg, Alexander

PY - 2021

Y1 - 2021

N2 - We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing treated with sumatriptan. The cases support previous notions that gastrointestinal comorbidities may be related to papulopustular lesions and that flushing may be related to neurogenic inflammation and migraine. The cases also imply that a new approach to rosacea management, based on endotypes and comorbidities, may be warranted.

AB - We present 2 cases of rosacea that were successfully managed with off-label treatment. The first is a case of painful, exuding papulopustular lesions of the nose treated with rifaximin, and the other is a case of severe, debilitating and painful flushing treated with sumatriptan. The cases support previous notions that gastrointestinal comorbidities may be related to papulopustular lesions and that flushing may be related to neurogenic inflammation and migraine. The cases also imply that a new approach to rosacea management, based on endotypes and comorbidities, may be warranted.

KW - Flushing

KW - Rifaximin

KW - Rosacea

KW - Sumatriptan

U2 - 10.1159/000511984

DO - 10.1159/000511984

M3 - Journal article

C2 - 33790755

VL - 13

SP - 121

EP - 128

JO - Case Reports in Dermatology

JF - Case Reports in Dermatology

SN - 1662-6567

IS - 1

ER -

Subtype-Specific Off-Label Treatment of Rosacea

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Keywords

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