Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Dominant optic atrophy in Denmark - report of 15 novel mutations in OPA1, using a strategy with a detection rate of 90%

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Identification of 3 novel VHL germ-line mutations in Danish VHL patients

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Detection of illness worry in the general population: A specific item on illness rumination improves the Whiteley Index

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Cardiac Troponin I and Incident Stroke in European Cohorts: Insights From the BiomarCaRE Project

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Repositioning of the global epicentre of non-optimal cholesterol

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Lena Sønder Snogdal
  • Niels Grarup
  • Karina Banasik
  • Mette Wod
  • Torben Jørgensen
  • Daniel Rinse Witte
  • Torsten Lauritzen
  • Aneta Aleksandra Nielsen
  • Ivan Brandslund
  • Cramer Christensen
  • Oluf Borbye Pedersen
  • Knud Bonnet Yderstræde
  • Henning Beck-Nielsen
  • Jan Erik Henriksen
  • Torben Hansen
  • Kurt Højlund
View graph of relations
Type 2 diabetes, obesity and insulin resistance are characterized by hypertriglyceridemia and ectopic accumulation of lipids in liver and skeletal muscle. AGPAT6 encodes a novel glycerol-3 phosphate acyltransferase, GPAT4, which catalyzes the first step in the de novo triglyceride synthesis. AGPAT6-deficient mice show lower weight and resistance to diet- and genetically induced obesity. Here, we examined whether common or low-frequency variants in AGPAT6 associate with type 2 diabetes or related metabolic traits in a Danish population.
Original languageEnglish
JournalB M C Medical Genetics
Volume14
Issue number1
Pages (from-to)113
ISSN1471-2350
DOIs
Publication statusPublished - 25 Oct 2013

ID: 40907234