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Streamline tractography for 3D mapping of axon bundle organization in one MRI voxel using ultra-high resolution synchrotron radiation imaging

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We present an efficient image analysis pipeline that enables us to reveal white matter organization in high-resolution 3D non-MRI structural datasets, in cases where a strict image segmentation is not required nor possible. We apply the method to a synchrotron X-ray holographic tomography scan from a healthy mouse sample, and show the organization of axon bundles in a region covering parts of the corpus callosum and the cingulum. The method has a potential to improve our general understanding of white matter organization and our ability to generate realistic phantoms for validation of microstructure modelling from low-resolution diffusion MRI scans.
Original languageEnglish
Title of host publicationProceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition
Number of pages3
PublisherThe International Society for Magnetic Resonance in Medicine
Publication dateAug 2020
Pages1-3
Article number0727
Publication statusPublished - Aug 2020
EventISMRM & SMRT Virtual Conference & Exhibition 2020 - Virtual conference
Duration: 8 Aug 202014 Aug 2020
https://www.ismrm.org/20m/

Conference

ConferenceISMRM & SMRT Virtual Conference & Exhibition 2020
LocationVirtual conference
Periode08/08/202014/08/2020
Internetadresse

Event

ISMRM & SMRT Virtual Conference & Exhibition 2020

08/08/202014/08/2020

Event: Conference

ID: 62005638