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Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes

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Harvard

Clementsen, P, Bisgaard, H, Pedersen, M, Permin, H, Struve-Christensen, E, Milman, N, Nüchel-Petersen, B & Norn, S 1989, 'Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes' Agents and Actions, vol. 27, no. 1-2, pp. 107-9.

APA

Clementsen, P., Bisgaard, H., Pedersen, M., Permin, H., Struve-Christensen, E., Milman, N., ... Norn, S. (1989). Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes. Agents and Actions, 27(1-2), 107-9.

CBE

Clementsen P, Bisgaard H, Pedersen M, Permin H, Struve-Christensen E, Milman N, Nüchel-Petersen B, Norn S. 1989. Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes. Agents and Actions. 27(1-2):107-9.

MLA

Vancouver

Clementsen P, Bisgaard H, Pedersen M, Permin H, Struve-Christensen E, Milman N et al. Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes. Agents and Actions. 1989 Apr;27(1-2):107-9.

Author

Clementsen, P ; Bisgaard, H ; Pedersen, M ; Permin, H ; Struve-Christensen, E ; Milman, N ; Nüchel-Petersen, B ; Norn, S. / Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes. In: Agents and Actions. 1989 ; Vol. 27, No. 1-2. pp. 107-9.

Bibtex

@article{06572b334ae14067bc392cc26c673334,
title = "Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes",
abstract = "Mediator release was examined from superficially lying cells in the airway epithelium obtained by bronchoalveolar lavage (BAL) in 13 non-atopic individuals. The BAL-cells were incubated (20 min, 37 degrees C) with Staphylococcus (Staph.) aureus or with human influenza A virus Staph. aureus was found to release histamine from cells from 7 of the 13 individuals and influenza A virus in 3 of 5 persons. Furthermore, Staph, aureus stimulated the BAL-cells to release leukotriene B4 in 7 of 11 subjects, whereas no release was found by influenza A virus in 7 examined persons. When cells from 4 persons were stimulated with Staph. aureus no release of leukotriene C4 was found. The mediator release caused by bacteria and virus might be of importance for the exacerbation of bronchial asthma in upper respiratory tract infections, since histamine is assumed to increase the epithelial permeability with entrance of allergens and other insulting particles, and leukotriene B4 facilitates airway inflammation.",
keywords = "Adult, Aged, Asthma, Female, Histamine Release, Humans, In Vitro Techniques, Influenza A virus, Leukotriene B4, Leukotrienes, Male, Middle Aged, Respiratory System, Respiratory Tract Infections, SRS-A, Staphylococcus aureus",
author = "P Clementsen and H Bisgaard and M Pedersen and H Permin and E Struve-Christensen and N Milman and B N{\"u}chel-Petersen and S Norn",
year = "1989",
month = "4",
language = "English",
volume = "27",
pages = "107--9",
journal = "Agents and Actions",
issn = "0065-4299",
publisher = "Birkhauser Verlag Basel",
number = "1-2",

}

RIS

TY - JOUR

T1 - Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes

AU - Clementsen, P

AU - Bisgaard, H

AU - Pedersen, M

AU - Permin, H

AU - Struve-Christensen, E

AU - Milman, N

AU - Nüchel-Petersen, B

AU - Norn, S

PY - 1989/4

Y1 - 1989/4

N2 - Mediator release was examined from superficially lying cells in the airway epithelium obtained by bronchoalveolar lavage (BAL) in 13 non-atopic individuals. The BAL-cells were incubated (20 min, 37 degrees C) with Staphylococcus (Staph.) aureus or with human influenza A virus Staph. aureus was found to release histamine from cells from 7 of the 13 individuals and influenza A virus in 3 of 5 persons. Furthermore, Staph, aureus stimulated the BAL-cells to release leukotriene B4 in 7 of 11 subjects, whereas no release was found by influenza A virus in 7 examined persons. When cells from 4 persons were stimulated with Staph. aureus no release of leukotriene C4 was found. The mediator release caused by bacteria and virus might be of importance for the exacerbation of bronchial asthma in upper respiratory tract infections, since histamine is assumed to increase the epithelial permeability with entrance of allergens and other insulting particles, and leukotriene B4 facilitates airway inflammation.

AB - Mediator release was examined from superficially lying cells in the airway epithelium obtained by bronchoalveolar lavage (BAL) in 13 non-atopic individuals. The BAL-cells were incubated (20 min, 37 degrees C) with Staphylococcus (Staph.) aureus or with human influenza A virus Staph. aureus was found to release histamine from cells from 7 of the 13 individuals and influenza A virus in 3 of 5 persons. Furthermore, Staph, aureus stimulated the BAL-cells to release leukotriene B4 in 7 of 11 subjects, whereas no release was found by influenza A virus in 7 examined persons. When cells from 4 persons were stimulated with Staph. aureus no release of leukotriene C4 was found. The mediator release caused by bacteria and virus might be of importance for the exacerbation of bronchial asthma in upper respiratory tract infections, since histamine is assumed to increase the epithelial permeability with entrance of allergens and other insulting particles, and leukotriene B4 facilitates airway inflammation.

KW - Adult

KW - Aged

KW - Asthma

KW - Female

KW - Histamine Release

KW - Humans

KW - In Vitro Techniques

KW - Influenza A virus

KW - Leukotriene B4

KW - Leukotrienes

KW - Male

KW - Middle Aged

KW - Respiratory System

KW - Respiratory Tract Infections

KW - SRS-A

KW - Staphylococcus aureus

M3 - Journal article

VL - 27

SP - 107

EP - 109

JO - Agents and Actions

JF - Agents and Actions

SN - 0065-4299

IS - 1-2

ER -

ID: 46041775