Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Spontaneous intracranial hypotension presenting with progressive cognitive decline

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Internal bowel herniation through a peritoneal defect between the right fallopian tube and right ovarian vessels

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Severe influenza in a paediatric patient with GATA2 deficiency and Emberger syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Severe acute hepatitis E infection presenting with acute abdomen and meningoencephalitis

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Severe hypophosphataemia following oral bisphosphonate treatment in a patient with osteoporosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Intracranial entrapment of a haemodialysis catheter guidewire

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Paracetamol use during pregnancy - a call for precautionary action

    Research output: Contribution to journalReviewResearchpeer-review

  2. Poor social support and loneliness in chronic headache: Prevalence and effect modifiers

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Health-related quality of life in tension-type headache: a population-based study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Guidelines of the International Headache Society for clinical trials with neuromodulation devices for the treatment of migraine

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

A 63-year-old woman presented with headache, progressive somnolence, neurocognitive decline and urinary incontinence through a year. Medical history was unremarkable except for hypertension and hypercholesterolaemia. Neurological examination was normal. Brain MRI showed findings typical for spontaneous intracranial hypotension (subdural fluid collection, pachymeningeal enhancement, brain sagging) and pituitary tumour. The patient's complaints improved dramatically but temporarily after treatment with each of repeated targeted as well as non-targeted blood patches and a trial with continuous intrathecal saline infusion. Extensive work up including repeated MRI-scans, radioisotope cisternographies, CT and T2-weighted MR myelography could not localise the leakage, but showed minor root-cysts at three levels. Finally, lateral decubitus digital subtraction dynamic myelography with subsequent CT myelography identified a tiny dural venous fistula at the fourth thoracic level. After surgical venous ligation, the patient fully recovered. Awareness of spontaneous dural leaks and their heterogeneous clinical picture are important and demands an extensive workup.

Original languageEnglish
Article numbere241285
JournalBMJ Case Reports
Volume14
Issue number7
Pages (from-to)1-5
Number of pages5
ISSN1757-790X
DOIs
Publication statusPublished - 21 Jul 2021

    Research areas

  • Cognitive Dysfunction/diagnosis, Female, Humans, Intracranial Hypotension/diagnosis, Magnetic Resonance Imaging, Middle Aged, Myelography, Neuroimaging

ID: 66964276