Spectral principal axes system (SPAS) and tuning of tensor-valued encoding for time-dependent anisotropic diffusion

Abstract

Tensor-valued diffusion encoding can be confounded by time-dependent diffusion (TDD). Matching sensitivity to TDD or tuning of b-tensors with different shapes is needed for unbiased microstructure assessment. We present a method for tuning linear tensor encoding (LTE) to spherical tensor encoding (STE), which could be optimized for different hardware constraints. Furthermore, we introduce the spectral principle axes system (SPAS), representing spectral anisotropy of STE. The SPAS LTEs could provide an alternative to tuning and enable disentangling effects of microscopic anisotropy and TDD, useful to correlate cell shape and size.
Original languageEnglish
Publication date12 May 2022
Publication statusPublished - 12 May 2022
EventJoint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting - London, Englnd, UK
Duration: 7 May 202212 May 2022
https://www.ismrm.org/22m/

Conference

ConferenceJoint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting
LocationLondon, Englnd, UK
Period07/05/202212/05/2022
Internet address

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