Somatosensory phenomena elicited by electrical stimulation of hippocampus: Insight into the ictal network

Torsten Vinding Merinder, György Rásonyi, Ioannis Tsiropoulos, Bo Jespersen, Philippe Ryvlin, Martin Fabricius, Sándor Beniczky

Abstract

Up to 11% of patients with mesial temporal lobe epilepsy experience somatosensory auras, although these structures do not have any somatosensory physiological representation. We present the case of a patient with left mesial temporal lobe epilepsy who had somatosensory auras on the right side of the body. Stereo-EEG recording demonstrated seizure onset in the left mesial temporal structures, with propagation to the sensory cortices, when the patient experienced the somatosensory aura. Direct electrical stimulation of both the left amygdala and the hippocampus elicited the patient's habitual, somatosensory aura, with afterdischarges propagating to sensory cortices. These unusual responses to cortical stimulation suggest that in patients with epilepsy, aberrant neural networks are established, which have an essential role in ictogenesis.

Original languageEnglish
JournalEpilepsy and Behavior
Volume14
Pages (from-to)100387
ISSN1525-5050
DOIs
Publication statusPublished - 2020

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