Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening

A Kjellman; O Akre; O Gustafsson; G Høyer-Hansen; H Lilja; U Norming; T Piironen; M Törnblom

doi:10.1111/j.1365-2796.2010.02284.x

Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening

A Kjellman, O Akre, O Gustafsson, G Høyer-Hansen, H Lilja, U Norming, T Piironen, M Törnblom

34 Citations (Scopus)

Abstract

The urokinase plasminogen activator (uPA) system is involved in tissue remodelling processes and is up-regulated in many types of malignancies. We investigated whether serum levels of different forms of soluble uPA receptor (suPAR) are associated with survival and in particular with prostate cancer and cardiovascular disease mortality.

Original language	English
Journal	Journal of Internal Medicine
Volume	269
Issue number	3
Pages (from-to)	299-305
Number of pages	7
ISSN	0954-6820
DOIs	https://doi.org/10.1111/j.1365-2796.2010.02284.x
Publication status	Published - 2011

Keywords

Aged
Cardiovascular Diseases
Early Detection of Cancer
Epidemiologic Methods
Humans
Male
Middle Aged
Prognosis
Prostatic Neoplasms
Receptors, Urokinase Plasminogen Activator
Sweden
Tumor Markers, Biological

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10.1111/j.1365-2796.2010.02284.x

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abstract = "The urokinase plasminogen activator (uPA) system is involved in tissue remodelling processes and is up-regulated in many types of malignancies. We investigated whether serum levels of different forms of soluble uPA receptor (suPAR) are associated with survival and in particular with prostate cancer and cardiovascular disease mortality.",

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T1 - Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening

AU - Kjellman, A

AU - Akre, O

AU - Gustafsson, O

AU - Høyer-Hansen, G

AU - Lilja, H

AU - Norming, U

AU - Piironen, T

AU - Törnblom, M

PY - 2011

Y1 - 2011

N2 - The urokinase plasminogen activator (uPA) system is involved in tissue remodelling processes and is up-regulated in many types of malignancies. We investigated whether serum levels of different forms of soluble uPA receptor (suPAR) are associated with survival and in particular with prostate cancer and cardiovascular disease mortality.

AB - The urokinase plasminogen activator (uPA) system is involved in tissue remodelling processes and is up-regulated in many types of malignancies. We investigated whether serum levels of different forms of soluble uPA receptor (suPAR) are associated with survival and in particular with prostate cancer and cardiovascular disease mortality.

KW - Aged

KW - Cardiovascular Diseases

KW - Early Detection of Cancer

KW - Epidemiologic Methods

KW - Humans

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Prostatic Neoplasms

KW - Receptors, Urokinase Plasminogen Activator

KW - Sweden

KW - Tumor Markers, Biological

UR - https://www.scopus.com/pages/publications/79951709761

U2 - 10.1111/j.1365-2796.2010.02284.x

DO - 10.1111/j.1365-2796.2010.02284.x

M3 - Journal article

C2 - 21138491

SN - 0954-6820

VL - 269

SP - 299

EP - 305

JO - Journal of Internal Medicine

JF - Journal of Internal Medicine

IS - 3

ER -

Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening

Abstract

Keywords

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