TY - JOUR
T1 - Social responsiveness in families with parental schizophrenia or bipolar disorder-The Danish High Risk and Resilience Study
AU - Veddum, Lotte
AU - Gregersen, Maja
AU - Andreassen, Anna Krogh
AU - Knudsen, Christina Bruun
AU - Brandt, Julie Marie
AU - Krantz, Mette Falkenberg
AU - Søndergaard, Anne
AU - Burton, Birgitte Klee
AU - Jepsen, Jens Richardt Møllegaard
AU - Hemager, Nicoline
AU - Thorup, Anne Amalie Elgaard
AU - Nordentoft, Merete
AU - Mors, Ole
AU - Bliksted, Vibeke
AU - Greve, Aja Neergaard
N1 - Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.
PY - 2023/5
Y1 - 2023/5
N2 - Schizophrenia and bipolar disorder are highly heritable severe mental disorders associated with social impairments. Moreover, partners to individuals with one of these disorders display poorer functioning and more psychopathology, but their social skills and the transgenerational transmission remains uninvestigated. Therefore, we aimed to examine social responsiveness in families with parental schizophrenia or bipolar disorder. The cohort consists of 11-year-old children with at least one parent with schizophrenia (n = 179) or bipolar disorder (n = 105) and population-based controls (PBC, n = 181). Children and parents were assessed with The Social Responsiveness Scale, Second Edition. Duration of time each parent and child have lived together was ascertained through interviews. Parents with schizophrenia and parents with bipolar disorder exhibited poorer social responsiveness compared with PBC parents. Parents with schizophrenia displayed poorer social responsiveness compared with parents with bipolar disorder. Schizophrenia co-parents exhibited poorer social responsiveness compared with bipolar co-parents and PBC co-parents. We found significant positive associations between parents' and children's social responsiveness, with no interaction effect of duration of time living together. Considering that social impairments are suggested as a vulnerability marker, this knowledge calls for increased attention towards vulnerable families, particularly those where both parents have social impairments.
AB - Schizophrenia and bipolar disorder are highly heritable severe mental disorders associated with social impairments. Moreover, partners to individuals with one of these disorders display poorer functioning and more psychopathology, but their social skills and the transgenerational transmission remains uninvestigated. Therefore, we aimed to examine social responsiveness in families with parental schizophrenia or bipolar disorder. The cohort consists of 11-year-old children with at least one parent with schizophrenia (n = 179) or bipolar disorder (n = 105) and population-based controls (PBC, n = 181). Children and parents were assessed with The Social Responsiveness Scale, Second Edition. Duration of time each parent and child have lived together was ascertained through interviews. Parents with schizophrenia and parents with bipolar disorder exhibited poorer social responsiveness compared with PBC parents. Parents with schizophrenia displayed poorer social responsiveness compared with parents with bipolar disorder. Schizophrenia co-parents exhibited poorer social responsiveness compared with bipolar co-parents and PBC co-parents. We found significant positive associations between parents' and children's social responsiveness, with no interaction effect of duration of time living together. Considering that social impairments are suggested as a vulnerability marker, this knowledge calls for increased attention towards vulnerable families, particularly those where both parents have social impairments.
KW - Familial high-risk
KW - Nonrandom mating
KW - Parental mental illness
KW - Social skills
KW - Transgenerational transmission
UR - http://www.scopus.com/inward/record.url?scp=85149659101&partnerID=8YFLogxK
U2 - 10.1016/j.psychres.2023.115140
DO - 10.1016/j.psychres.2023.115140
M3 - Journal article
C2 - 36898170
SN - 0165-1781
VL - 323
SP - 115140
JO - Psychiatry Research
JF - Psychiatry Research
M1 - 115140
ER -