Sinonasal schwannoma--a clinicopathological analysis of five rare cases

K H Mey, C Buchwald, S Daugaard, J U Prause

45 Citations (Scopus)

Abstract

Schwannoma of the nasal cavity or the sinuses is a rare condition. We report a small series of five consecutive patients; three males and two females, age range 22-81 years, all Caucasian. Symptoms were typically non-specific, and the tumours were often quite large when diagnosed, being locally infiltrating and even destructive. Histologically, the tumours were remarkable by sparse occurrence of Antoni type B areas and lack of encapsulation. Four cases were benign; however, one case of melanotic schwannoma, exhibited malignant transformation. Two of the patients had intracranial involvement, but with an intact dura. All tumours were treated surgically; only the malignant case received adjuvant radiotherapy. Patients were followed from five months to 15 years, with a median of 57 months. The benign cases have so far shown good prognosis without recurrences; however, in the case of the melanotic schwannoma a fatal malignant transformation was seen 13 years after initial diagnosis. On the basis of our review early detection and complete surgical removal is recommended.

Original languageEnglish
JournalRhinology
Volume44
Issue number1
Pages (from-to)46-52
Number of pages7
ISSN0300-0729
Publication statusPublished - Mar 2006
Externally publishedYes

Keywords

  • Adult
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurilemmoma/pathology
  • Nose Neoplasms/pathology
  • Paranasal Sinus Neoplasms/pathology

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