Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Simultaneous 31P NMR spectroscopy and EMG in exercising and recovering human skeletal muscle: technical aspects

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Quantification of cerebral perfusion and cerebrovascular reserve using Turbo-QUASAR arterial spin labeling MRI

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Coil profile estimation strategies for parallel imaging with hyperpolarized 13 C MRI

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Gamma-aminobutyric acid edited echo-planar spectroscopic imaging (EPSI) with MEGA-sLASER at 7T

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Comparison of prospective head motion correction with NMR field probes and an optical tracking system

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Improved calculation of the equilibrium magnetization of arterial blood in arterial spin labeling

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. The effect of passive stretching on delayed onset muscle soreness, and other detrimental effects following eccentric exercise.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Simultaneous 31P-NMR spectroscopy and EMG in exercising and recovering human skeletal muscle: a correlation study.

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
The bioenergetics of human skeletal muscle can be studied by 31P NMR spectroscopy (31P-MRS) and by surface electromyography (SEMG). Simultaneous 31P-MRS and SEMG permit accurate and noninvasive studies of the correlation between metabolic and electrical changes in exercising and recovering human skeletal muscle, a relationship that is still poorly understood. This study describes the optimization of skeletal muscle 31P-MRS in a whole-body magnet, involving surface coil design, utilization of adiabatic radio frequency pulses and advanced time-domain fitting, to the technical design of SEMG. A nonmagnetic ergometer was used for ankle dorsiflexions that activated only the anterior tibial muscle as verified by post exercise imaging. The coil design and the adiabatic sech/tanh pulse improved sensitivity by 45% and 56% respectively, compared with standard techniques. Simultaneous electromyographic recordings did not deteriorate the NMR spectra. The VARPRO time domain fitting routine was very suitable for estimating 31P muscle spectra. With these methods it was possible to accurately estimate parameters describing metabolic and electrical changes during rest, exercise and the entire recovery period with a 20-s time resolution on a standard 1.5 T whole-body NMR scanner.
Original languageEnglish
JournalMagnetic Resonance in Medicine
Volume31
Issue number2
Pages (from-to)93-102
Number of pages10
ISSN0740-3194
Publication statusPublished - 1994

    Research areas

  • Ankle Joint, Electromyography, Ergometry, Fatigue, Humans, Isometric Contraction, Magnetic Resonance Spectroscopy, Movement, Muscles, Phosphocreatine, Phosphorus, Physical Exertion, Rest

ID: 32500301