Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Significantly increased risk of all-cause mortality among cardiac patients feeling lonely

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Valve regurgitation in patients surviving endocarditis and the subsequent risk of heart failure

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Alcohol septal ablation in patients with severe septal hypertrophy

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Interaction of ischaemic postconditioning and thrombectomy in patients with ST-elevation myocardial infarction

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Outcome after heart-lung or lung transplantation in patients with Eisenmenger syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Role of the lymphatic vasculature in cardiovascular medicine

    Research output: Contribution to journalReviewResearchpeer-review

  1. Questionnaire measuring patient participation in health care: Scale development and psychometric evaluation

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Cognitive impairment and psychopathology in out-of-hospital cardiac arrest survivors in Denmark: The REVIVAL cohort study protocol

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. A place of understanding: Patients' lived experiences of participating in a sexual rehabilitation programme after heart disease

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. What to expect after open heart valve surgery? Changes in health-related quality of life

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

OBJECTIVE: To explore whether living alone and loneliness 1) are associated with poor patient-reported outcomes at hospital discharge and 2) predict cardiac events and mortality 1 year after hospital discharge in women and men with ischaemic heart disease, arrhythmia, heart failure or heart valve disease.

METHODS: A national cross-sectional survey including patients with known cardiac disease at hospital discharge combined with national register data at baseline and 1-year follow-up. Loneliness was evaluated using one self-reported question, and information on cohabitation was available from national registers. Patient-reported outcomes were Short Form-12, Hospital Anxiety and Depression Scale and HeartQoL. Clinical outcomes were 1-year cardiac events (myocardial infarction, stroke, cardiac arrest, ventricular tachycardia/fibrillation) and all-cause mortality from national registers.

RESULTS: A total of 13 443 patients (53%) with ischaemic heart disease, arrhythmia, heart failure or heart valve disease completed the survey. Of these, 70% were male, and mean age was 66.1 among women and 64.9 among men. Across cardiac diagnoses, loneliness was associated with significantly poorer patient-reported outcomes in men and women. Loneliness predicted all-cause mortality among women and men (HR 2.92 (95% CI 1.55 to 5.49) and HR 2.14 (95% CI 1.43 to 3.22), respectively). Living alone predicted cardiac events in men only (HR 1.39 (95% CI 1.05 to 1.85)).

CONCLUSIONS: A strong association between loneliness and poor patient-reported outcomes and 1-year mortality was found in both men and women across cardiac diagnoses. The results suggest that loneliness should be a priority for public health initiatives, and should also be included in clinical risk assessment in cardiac patients.

Original languageEnglish
JournalHeart (British Cardiac Society)
Volume106
Issue number2
Pages (from-to)140-146
Number of pages7
ISSN1355-6037
DOIs
Publication statusPublished - Jan 2020

    Research areas

  • coronary artery disease, epidemiology, heart failure, valvular heart disease

ID: 59135364