Should dosing of rocuronium in obese patients be based on ideal or corrected body weight?

Christian S Meyhoff, Jørgen Lund, Morten T Jenstrup, Casper Claudius, Anne M Sørensen, Jørgen Viby-Mogensen, Lars S Rasmussen

100 Citations (Scopus)

Abstract

Pharmacokinetic studies in obese patients suggest that dosing of rocuronium should be based on ideal body weight (IBW). This may, however, result in a prolonged onset time or compromised conditions for tracheal intubation. In this study, we compared onset time, conditions for tracheal intubation, and duration of action in obese patients when the intubation dose of rocuronium was based on three different weight corrections.
Original languageEnglish
JournalAnesthesia and Analgesia
Volume109
Issue number3
Pages (from-to)787-92
Number of pages6
ISSN0003-2999
DOIs
Publication statusPublished - Sept 2009

Keywords

  • Adult
  • Androstanols
  • Anesthesia Recovery Period
  • Anesthetics, Intravenous
  • Body Mass Index
  • Body Weight
  • Female
  • Gastric Bypass
  • Humans
  • Male
  • Middle Aged
  • Neuromuscular Nondepolarizing Agents
  • Obesity
  • Piperidines
  • Propofol

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