Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network

Pasoon Hellamand; Marleen G H Van de Sande; Lykke Midtbøll Ørnbjerg; Thomas Klausch; Michael Nurmohamed; R Van Vollenhoven; D.C. Nordström; Anna-Mari Hokkanen; MJ Santos; Elsa Vieira-Sousa; A. G. Loft; Bente Glintborg; Merete Lund Hetland; U Lindström; Johan Karlsson Wallman; Martin Michelsen; Adrian Ciurea; Michael J Nissen; Catalin Codreanu; C Moogosan; Gary J Macfarlane; Gareth T Jones; Karin Laas; Z Roter; M Tomsic; I Castrejon; M Pombo-Suarez; B Gudbjörnsson; Arni Jon Geirsson; Eirik K. Kristianslund; Jirí Vencovský; Lucie Nekvindova; B Zengin; Seth Guller; Mikkel Østergaard; I Van der Horst- Bruinsma

Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network

Pasoon Hellamand
, Marleen G H Van de Sande
, Lykke Midtbøll Ørnbjerg
, Thomas Klausch
, Michael Nurmohamed
, R Van Vollenhoven
, D.C. Nordström
, Anna-Mari Hokkanen
, MJ Santos
, Elsa Vieira-Sousa
, A. G. Loft
, Bente Glintborg
, Merete Lund Hetland
, U Lindström
, Johan Karlsson Wallman
, Martin Michelsen
, Adrian Ciurea
, Michael J Nissen
, Catalin Codreanu
, C Moogosan

Gary J Macfarlane, Gareth T Jones, Karin Laas, Z Roter, M Tomsic, I Castrejon, M Pombo-Suarez, B Gudbjörnsson, Arni Jon Geirsson, Eirik K. Kristianslund, Jirí Vencovský, Lucie Nekvindova, B Zengin, Seth Guller, Mikkel Østergaard, I Van der Horst- Bruinsma

Abstract

Background:
Evidence demonstrates sex differences in disease presentation, physical function, treatment response and drug retention in patients with psoriatic arthritis (PsA). Data from observational cohort studies indicate female sex is associated with reduced effectiveness of tumor necrosis factor inhibitors (TNFis). Although, conflicting results are also reported3,4. We sought to validate prior studies using data from a large multinational cohort based on real-life clinical practice.

Original language	English
Publication date	2022
Publication status	Published - 2022
Event	The Thirteenth International Congress on Spondyloarthritides - Ghent, Belgium Duration: 7 Sept 2022 → 9 Sept 2022

Conference

Conference	The Thirteenth International Congress on Spondyloarthritides
Country/Territory	Belgium
City	Ghent
Period	07/09/2022 → 09/09/2022

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Hellamand, P., Van de Sande, M. G. H., Ørnbjerg, L. M., Klausch, T., Nurmohamed, M., Van Vollenhoven, R., Nordström, D. C., Hokkanen, A.-M., Santos, MJ., Vieira-Sousa, E., Loft, A. G., Glintborg, B., Hetland, M. L., Lindström, U., Wallman, J. K., Michelsen, M., Ciurea, A., Nissen, M. J., Codreanu, C., ... Van der Horst- Bruinsma, I. (2022). Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network. Clinical and Experimental Rheumatology . Abstract from The Thirteenth International Congress on Spondyloarthritides, Ghent, Belgium.

Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network. / Hellamand, Pasoon; Van de Sande, Marleen G H; Ørnbjerg, Lykke Midtbøll et al.
2022. Clinical and Experimental Rheumatology Abstract from The Thirteenth International Congress on Spondyloarthritides, Ghent, Belgium.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Hellamand, P, Van de Sande, MGH, Ørnbjerg, LM, Klausch, T, Nurmohamed, M, Van Vollenhoven, R, Nordström, DC, Hokkanen, A-M, Santos, MJ, Vieira-Sousa, E, Loft, AG, Glintborg, B , Hetland, ML, Lindström, U, Wallman, JK, Michelsen, M, Ciurea, A, Nissen, MJ, Codreanu, C, Moogosan, C, Macfarlane, GJ, Jones, GT, Laas, K, Roter, Z, Tomsic, M, Castrejon, I, Pombo-Suarez, M, Gudbjörnsson, B, Geirsson, AJ, Kristianslund, EK, Vencovský, J, Nekvindova, L, Zengin, B, Guller, S, Østergaard, M & Van der Horst- Bruinsma, I 2022, 'Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network', The Thirteenth International Congress on Spondyloarthritides, Ghent, Belgium, 07/09/2022 - 09/09/2022 pp. Clinical and Experimental Rheumatology .

Hellamand P, Van de Sande MGH, Ørnbjerg LM, Klausch T, Nurmohamed M, Van Vollenhoven R et al.. Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network. 2022. Abstract from The Thirteenth International Congress on Spondyloarthritides, Ghent, Belgium.

Hellamand, Pasoon ; Van de Sande, Marleen G H ; Ørnbjerg, Lykke Midtbøll et al. / Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network. Abstract from The Thirteenth International Congress on Spondyloarthritides, Ghent, Belgium.

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title = "Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network",

abstract = "Background: Evidence demonstrates sex differences in disease presentation, physical function, treatment response and drug retention in patients with psoriatic arthritis (PsA). Data from observational cohort studies indicate female sex is associated with reduced effectiveness of tumor necrosis factor inhibitors (TNFis). Although, conflicting results are also reported3,4. We sought to validate prior studies using data from a large multinational cohort based on real-life clinical practice.",

author = "Pasoon Hellamand and \{Van de Sande\}, \{Marleen G H\} and {\O}rnbjerg, \{Lykke Midtb{\o}ll\} and Thomas Klausch and Michael Nurmohamed and \{Van Vollenhoven\}, R and D.C. Nordstr{\"o}m and Anna-Mari Hokkanen and MJ Santos and Elsa Vieira-Sousa and Loft, \{A. G.\} and Bente Glintborg and Hetland, \{Merete Lund\} and U Lindstr{\"o}m and Wallman, \{Johan Karlsson\} and Martin Michelsen and Adrian Ciurea and Nissen, \{Michael J\} and Catalin Codreanu and C Moogosan and Macfarlane, \{Gary J\} and Jones, \{Gareth T\} and Karin Laas and Z Roter and M Tomsic and I Castrejon and M Pombo-Suarez and B Gudbj{\"o}rnsson and Geirsson, \{Arni Jon\} and Kristianslund, \{Eirik K.\} and Jir{\'i} Vencovsk{\'y} and Lucie Nekvindova and B Zengin and Seth Guller and Mikkel {\O}stergaard and \{Van der Horst- Bruinsma\}, I",

note = "COPECARE; The Thirteenth International Congress on Spondyloarthritides ; Conference date: 07-09-2022 Through 09-09-2022",

year = "2022",

language = "English",

pages = "Clinical and Experimental Rheumatology ",

}

TY - ABST

T1 - Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in axial spondyloarthritis; results from fifteen countries in the European spondyloarthritis (EuroSpA) research collaboration network

AU - Hellamand, Pasoon

AU - Van de Sande, Marleen G H

AU - Ørnbjerg, Lykke Midtbøll

AU - Klausch, Thomas

AU - Nurmohamed, Michael

AU - Van Vollenhoven, R

AU - Nordström, D.C.

AU - Hokkanen, Anna-Mari

AU - Santos, MJ

AU - Vieira-Sousa, Elsa

AU - Loft, A. G.

AU - Glintborg, Bente

AU - Hetland, Merete Lund

AU - Lindström, U

AU - Wallman, Johan Karlsson

AU - Michelsen, Martin

AU - Ciurea, Adrian

AU - Nissen, Michael J

AU - Codreanu, Catalin

AU - Moogosan, C

AU - Macfarlane, Gary J

AU - Jones, Gareth T

AU - Laas, Karin

AU - Roter, Z

AU - Tomsic, M

AU - Castrejon, I

AU - Pombo-Suarez, M

AU - Gudbjörnsson, B

AU - Geirsson, Arni Jon

AU - Kristianslund, Eirik K.

AU - Vencovský, Jirí

AU - Nekvindova, Lucie

AU - Zengin, B

AU - Guller, Seth

AU - Østergaard, Mikkel

AU - Van der Horst- Bruinsma, I

N1 - COPECARE

PY - 2022

Y1 - 2022

N2 - Background: Evidence demonstrates sex differences in disease presentation, physical function, treatment response and drug retention in patients with psoriatic arthritis (PsA). Data from observational cohort studies indicate female sex is associated with reduced effectiveness of tumor necrosis factor inhibitors (TNFis). Although, conflicting results are also reported3,4. We sought to validate prior studies using data from a large multinational cohort based on real-life clinical practice.

AB - Background: Evidence demonstrates sex differences in disease presentation, physical function, treatment response and drug retention in patients with psoriatic arthritis (PsA). Data from observational cohort studies indicate female sex is associated with reduced effectiveness of tumor necrosis factor inhibitors (TNFis). Although, conflicting results are also reported3,4. We sought to validate prior studies using data from a large multinational cohort based on real-life clinical practice.

M3 - Conference abstract for conference

SP - Clinical and Experimental Rheumatology

T2 - The Thirteenth International Congress on Spondyloarthritides

Y2 - 7 September 2022 through 9 September 2022

ER -