Sex differences in the effectiveness of first-line tumor necrosis factor inhibitors in psoriatic arthritis; results from thirteen countries in the European spondyloarthritis (EuroSpA) research collaboration network

Pasoon Hellamand, Marleen G H Van de Sande, Lykke Midtbøll Ørnbjerg, Thomas Klausch, N Trokovic, Tuulikki Sokka-Isler, R Van Vollenhoven, D.C. Nordström, MJ Santos, Elsa Vieira-Sousa, A. G. Loft, Bente Glintborg, Mikkel Østergaard, U Lindström, Johan Karlsson Wallman, Brigitte Michelsen, B. Moeller, Raphael Micheroli, Catalin Codreanu, C MoogosanKarin Laas, Z Roter, M Tomsic, I Castrejon, M Pombo-Suarez, B Gudbjörnsson, T Love, Karen Minde Fagerli, K. Pavelka, Jakub Závada, G Kenar, H Yarkan-Tugsai, Merete Lund Hetland, I Van der Horst- Bruinsma

Abstract

Background:
Evidence demonstrates sex differences in disease presentation, physical function, treatment response and drug retention in patients with psoriatic arthritis (PsA). Data from observational cohort studies indicate female sex is associated with reduced effectiveness of tumor necrosis factor inhibitors (TNFis)1,2. Although, conflicting results are also reported3,4. We sought to validate prior studies using data from a large multinational cohort based on real-life clinical practice.
Original languageEnglish
Publication date2022
Publication statusPublished - 2022
EventThe Thirteenth International Congress on Spondyloarthritides - Ghent, Belgium
Duration: 7 Sept 20229 Sept 2022

Conference

ConferenceThe Thirteenth International Congress on Spondyloarthritides
Country/TerritoryBelgium
CityGhent
Period07/09/202209/09/2022

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