Abstract
A 55-y-old male developed severe metabolic acidosis and renal failure during tenofovir therapy. Increased tenofovir exposure due to low body weight and chronic stable renal insufficiency could have enhanced the risk of nephrotoxicity, and creatinine clearance should be estimated before initiation of tenofovir.
| Original language | English |
|---|---|
| Journal | Scandinavian Journal of Infectious Diseases |
| Volume | 36 |
| Issue number | 5 |
| Pages (from-to) | 389-92 |
| Number of pages | 4 |
| ISSN | 0036-5548 |
| DOIs | |
| Publication status | Published - 2004 |
| Externally published | Yes |
Keywords
- Acidosis, Lactic/chemically induced
- Acute Kidney Injury/chemically induced
- Adenine/administration & dosage
- HIV Infections/complications
- Humans
- Kidney Function Tests
- Male
- Middle Aged
- Organophosphonates
- Organophosphorus Compounds/administration & dosage
- Prognosis
- Reverse Transcriptase Inhibitors/adverse effects
- Risk Assessment
- Severity of Illness Index
- Tenofovir
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