Severe iron intoxication treated with exchange transfusion

M Carlsson, D Cortes, S Jepsen, T Kanstrup

9 Citations (Scopus)


An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.
Original languageEnglish
JournalArchives of Disease in Childhood. Fetal and Neonatal Edition
Issue number4
Pages (from-to)321-2
Number of pages1
Publication statusPublished - 2008


  • Deferoxamine
  • Drug Therapy, Combination
  • Exchange Transfusion, Whole Blood
  • Female
  • Humans
  • Infant
  • Intensive Care
  • Iron
  • Siderophores


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