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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Severe foetal anaemia caused by undetected alloimmunisation in a RhD-positive pregnant woman

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The incidence of haemolytic disease of the foetus or newborn (HDFN) has decreased considerably in Denmark since the introduction of routine administration of prophylactic anti-D immunoglobulin to RhD-negative pregnant women carrying a RhD-positive foetus. RhD-positive pregnant women are screened for irregular antibodies only in the first trimester of their pregnancy, as their risk of clinically relevant immunisation during pregnancy has been considered very low. This is a case report of severe undetected alloimmunisation causing fatal HDFN after the first trimester in a RhD-positive woman.

Translated title of the contributionSevere foetal anaemia caused by undetected alloimmunisation in a RhD-positive pregnant woman
Original languageDanish
JournalUgeskrift for Laeger
Volume183
Issue number32
ISSN0041-5782
Publication statusPublished - 9 Aug 2021

ID: 69076009