Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease

F Nicoletti; I Conget; M Di Mauro; R Di Marco; M C Mazzarino; K Bendtzen; A Messina; R Gomis

doi:10.1007/s00125-002-0879-5

Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease

F Nicoletti, I Conget, M Di Mauro, R Di Marco, M C Mazzarino, K Bendtzen, A Messina, R Gomis

149 Citations (Scopus)

Abstract

Chemokines are chemotactic cytokines controlling the recruitment of leukocytes from the blood by regulating integrin adhesiveness. It has been shown that the migration of CD4+Th1 and CD4+Th2 cells is governed by specific chemokines. Increasing evidence suggests that the CD4+Th1 cheomoattractant chemokine CXCL10, also termed Interferon (IFN)-gamma -inducible protein (IP)-10 is pathogenetically involved in several immunoinflammatory and autoimmune diseases.

Original language	English
Journal	Diabetologia
Volume	45
Issue number	8
Pages (from-to)	1107-10
Number of pages	4
ISSN	0012-186X
DOIs	https://doi.org/10.1007/s00125-002-0879-5
Publication status	Published - 1 Aug 2002

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Nicoletti, F., Conget, I., Di Mauro, M., Di Marco, R., Mazzarino, M. C., Bendtzen, K., Messina, A., & Gomis, R. (2002). Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease. Diabetologia, 45(8), 1107-10. https://doi.org/10.1007/s00125-002-0879-5

Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease. / Nicoletti, F; Conget, I; Di Mauro, M et al.
In: Diabetologia, Vol. 45, No. 8, 01.08.2002, p. 1107-10.

Research output: Contribution to journal › Journal article › Research › peer-review

Nicoletti, F, Conget, I, Di Mauro, M, Di Marco, R, Mazzarino, MC, Bendtzen, K, Messina, A & Gomis, R 2002, 'Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease', Diabetologia, vol. 45, no. 8, pp. 1107-10. https://doi.org/10.1007/s00125-002-0879-5

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abstract = "Chemokines are chemotactic cytokines controlling the recruitment of leukocytes from the blood by regulating integrin adhesiveness. It has been shown that the migration of CD4+Th1 and CD4+Th2 cells is governed by specific chemokines. Increasing evidence suggests that the CD4+Th1 cheomoattractant chemokine CXCL10, also termed Interferon (IFN)-gamma -inducible protein (IP)-10 is pathogenetically involved in several immunoinflammatory and autoimmune diseases.",

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AU - Di Mauro, M

AU - Di Marco, R

AU - Mazzarino, M C

AU - Bendtzen, K

AU - Messina, A

AU - Gomis, R

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AB - Chemokines are chemotactic cytokines controlling the recruitment of leukocytes from the blood by regulating integrin adhesiveness. It has been shown that the migration of CD4+Th1 and CD4+Th2 cells is governed by specific chemokines. Increasing evidence suggests that the CD4+Th1 cheomoattractant chemokine CXCL10, also termed Interferon (IFN)-gamma -inducible protein (IP)-10 is pathogenetically involved in several immunoinflammatory and autoimmune diseases.

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Serum concentrations of the interferon-gamma-inducible chemokine IP-10/CXCL10 are augmented in both newly diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease

Abstract

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