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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

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  1. Novel functions of the luteinizing hormone/chorionic gonadotropin receptor in prostate cancer cells and patients

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  2. Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers

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  3. Inflammation, non-endothelial dependent coronary microvascular function and diastolic function-Are they linked?

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  4. Lipidomics of human adipose tissue reveals diversity between body areas

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  1. Plasmodium falciparum-CD36 Structure-Function Relationships Defined by Ortholog Scanning Mutagenesis

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  2. Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria

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  • Philip Bejon
  • Louise Turner
  • Thomas Lavstsen
  • Gerald Kennedy Cham Kpu
  • Ally Olotu
  • Chris J Drakeley
  • Marc Lievens
  • Johan Vekemans
  • Barbara Savarese
  • John Lusingu
  • Lorenz von Seidlein
  • Peter H. Bull
  • Kevin Marsh
  • Thor G Theander
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Malaria transmission may be considered to be homogenous with well-mixed parasite populations (as in the classic Ross/Macdonald models). Marked fine-scale heterogeneity of transmission has been observed in the field (i.e., over a few kilometres), but there are relatively few data on the degree of mixing. Since the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) is highly polymorphic, the host's serological responses may be used to infer exposure to parasite sub-populations.
Original languageEnglish
JournalP L o S One
Volume6
Issue number6
Pages (from-to)e21711
ISSN1932-6203
DOIs
Publication statusPublished - 1 Jan 2011

    Research areas

  • Aging, Animals, Antibody Formation, Cluster Analysis, Humans, Infant, Malaria, Plasmodium falciparum, Principal Component Analysis, Protozoan Proteins, Serologic Tests, Time Factors

ID: 32767596