TY - JOUR
T1 - Sensorimotor gating deficits in multiple system atrophy
T2 - Comparison with Parkinson's disease and idiopathic REM sleep behavior disorder
AU - Zoetmulder, Marielle
AU - Biernat, Heidi Bryde
AU - Nikolic, Miki
AU - Korbo, Lise
AU - Jennum, Poul Jørgen
N1 - Copyright © 2013 Elsevier Ltd. All rights reserved.
PY - 2014/3
Y1 - 2014/3
N2 - Prepulse inhibition (PPI) of the auditory blink reflex is a measure of sensorimotor gating, which reflects an organism's ability to filter out irrelevant sensory information. PPI has never been studied in patients with multiple system atrophy (MSA), although sensorimotor deficits are frequently associated with synucleinopathies. We investigated whether alterations in PPI were more pronounced in MSA compared with Parkinson's disease (PD), idiopathic rapid eye movement sleep behavior disorder (iRBD) and healthy controls.
AB - Prepulse inhibition (PPI) of the auditory blink reflex is a measure of sensorimotor gating, which reflects an organism's ability to filter out irrelevant sensory information. PPI has never been studied in patients with multiple system atrophy (MSA), although sensorimotor deficits are frequently associated with synucleinopathies. We investigated whether alterations in PPI were more pronounced in MSA compared with Parkinson's disease (PD), idiopathic rapid eye movement sleep behavior disorder (iRBD) and healthy controls.
U2 - 10.1016/j.parkreldis.2013.11.018
DO - 10.1016/j.parkreldis.2013.11.018
M3 - Journal article
C2 - 24355363
SN - 1353-8020
VL - 20
SP - 297
EP - 302
JO - Parkinsonism & related disorders
JF - Parkinsonism & related disorders
IS - 3
ER -