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Selected testosterone-related diseases in women who have given birth to a child with infantile autism

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@article{2e4245f0640a11df9344000ea68e967b,
title = "Selected testosterone-related diseases in women who have given birth to a child with infantile autism",
abstract = "AIM: The objective of the current study was to compare the prevalence of three testosterone-related cancer diseases in the mothers of 111 individuals diagnosed as children with infantile autism (IA) with a matched comparison group of mothers of 330 children from the general population. METHOD: All mothers were screened through the nationwide Danish National Hospital Register. We inquired about breast-, uterine-, and ovarian cancer diseases during an observation period of 27 years. RESULTS: At follow up a similar proportion of case and control mothers had a diagnosis of any cancer disease: 6.3% vs 8.5%. In addition, no single cancer disease was significantly more frequent among mothers of children with IA. CONCLUSION: Our study provides no support for an (eventually androgen-mediated) increased rate of cancer in mothers of persons with IA.",
author = "Svend-Erik Mouridsen and Bente Rich and Torben Isager",
note = "Keywords: Adult; Age Factors; Aged; Aged, 80 and over; Autistic Disorder; Breast Neoplasms; Child; Child of Impaired Parents; Child, Preschool; Denmark; Female; Follow-Up Studies; Genital Neoplasms, Female; Humans; Male; Middle Aged; Mothers; Ovarian Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Sex Distribution; Testosterone; Uterine Neoplasms",
year = "2009",
doi = "10.1111/j.1440-1819.2009.01997.x",
language = "English",
volume = "63",
pages = "586--90",
journal = "Psychiatry and Clinical Neurosciences",
issn = "1323-1316",
publisher = "Wiley-Blackwell Publishing Asia",
number = "4",

}

RIS

TY - JOUR

T1 - Selected testosterone-related diseases in women who have given birth to a child with infantile autism

AU - Mouridsen, Svend-Erik

AU - Rich, Bente

AU - Isager, Torben

N1 - Keywords: Adult; Age Factors; Aged; Aged, 80 and over; Autistic Disorder; Breast Neoplasms; Child; Child of Impaired Parents; Child, Preschool; Denmark; Female; Follow-Up Studies; Genital Neoplasms, Female; Humans; Male; Middle Aged; Mothers; Ovarian Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Sex Distribution; Testosterone; Uterine Neoplasms

PY - 2009

Y1 - 2009

N2 - AIM: The objective of the current study was to compare the prevalence of three testosterone-related cancer diseases in the mothers of 111 individuals diagnosed as children with infantile autism (IA) with a matched comparison group of mothers of 330 children from the general population. METHOD: All mothers were screened through the nationwide Danish National Hospital Register. We inquired about breast-, uterine-, and ovarian cancer diseases during an observation period of 27 years. RESULTS: At follow up a similar proportion of case and control mothers had a diagnosis of any cancer disease: 6.3% vs 8.5%. In addition, no single cancer disease was significantly more frequent among mothers of children with IA. CONCLUSION: Our study provides no support for an (eventually androgen-mediated) increased rate of cancer in mothers of persons with IA.

AB - AIM: The objective of the current study was to compare the prevalence of three testosterone-related cancer diseases in the mothers of 111 individuals diagnosed as children with infantile autism (IA) with a matched comparison group of mothers of 330 children from the general population. METHOD: All mothers were screened through the nationwide Danish National Hospital Register. We inquired about breast-, uterine-, and ovarian cancer diseases during an observation period of 27 years. RESULTS: At follow up a similar proportion of case and control mothers had a diagnosis of any cancer disease: 6.3% vs 8.5%. In addition, no single cancer disease was significantly more frequent among mothers of children with IA. CONCLUSION: Our study provides no support for an (eventually androgen-mediated) increased rate of cancer in mothers of persons with IA.

U2 - 10.1111/j.1440-1819.2009.01997.x

DO - 10.1111/j.1440-1819.2009.01997.x

M3 - Journal article

C2 - 19659562

VL - 63

SP - 586

EP - 590

JO - Psychiatry and Clinical Neurosciences

JF - Psychiatry and Clinical Neurosciences

SN - 1323-1316

IS - 4

ER -

ID: 171664