Screening of KCNN3 in patients with early-onset lone atrial fibrillation

Morten S Olesen; Javad Jabbari; Anders G Holst; Jonas B Nielsen; Daniel A Steinbrüchel; Thomas Jespersen; Stig Haunsø; Jesper H Svendsen

doi:10.1093/europace/eur007

Screening of KCNN3 in patients with early-onset lone atrial fibrillation

Morten S Olesen, Javad Jabbari, Anders G Holst, Jonas B Nielsen, Daniel A Steinbrüchel, Thomas Jespersen, Stig Haunsø, Jesper H Svendsen

44 Citations (Scopus)

Abstract

The aim of this study was to screen KCNN3 encoding the small-conductance calcium-activated K+ channel (SK3) in lone atrial fibrillation patients. Atrial fibrillation (AF) is the most common cardiac arrhythmia. A genome-wide association study has recently associated an intronic single-nucleotide polymorphism (SNP) in KCNN3 with lone AF.

Original language	English
Journal	Europace
Volume	13
Issue number	7
Pages (from-to)	963-7
Number of pages	5
ISSN	1099-5129
DOIs	https://doi.org/10.1093/europace/eur007
Publication status	Published - 2011

Keywords

Adult
Age of Onset
Atrial Fibrillation
Case-Control Studies
Cohort Studies
Denmark
Electrocardiography
Exons
Female
Genetic Testing
Genotype
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide
Small-Conductance Calcium-Activated Potassium Channels

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10.1093/europace/eur007

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title = "Screening of KCNN3 in patients with early-onset lone atrial fibrillation",

abstract = "The aim of this study was to screen KCNN3 encoding the small-conductance calcium-activated K+ channel (SK3) in lone atrial fibrillation patients. Atrial fibrillation (AF) is the most common cardiac arrhythmia. A genome-wide association study has recently associated an intronic single-nucleotide polymorphism (SNP) in KCNN3 with lone AF.",

keywords = "Adult, Age of Onset, Atrial Fibrillation, Case-Control Studies, Cohort Studies, Denmark, Electrocardiography, Exons, Female, Genetic Testing, Genotype, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Small-Conductance Calcium-Activated Potassium Channels",

author = "Olesen, \{Morten S\} and Javad Jabbari and Holst, \{Anders G\} and Nielsen, \{Jonas B\} and Steinbr{\"u}chel, \{Daniel A\} and Thomas Jespersen and Stig Hauns{\o} and Svendsen, \{Jesper H\}",

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doi = "10.1093/europace/eur007",

language = "English",

volume = "13",

pages = "963--7",

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T1 - Screening of KCNN3 in patients with early-onset lone atrial fibrillation

AU - Olesen, Morten S

AU - Jabbari, Javad

AU - Holst, Anders G

AU - Nielsen, Jonas B

AU - Steinbrüchel, Daniel A

AU - Jespersen, Thomas

AU - Haunsø, Stig

AU - Svendsen, Jesper H

PY - 2011

Y1 - 2011

N2 - The aim of this study was to screen KCNN3 encoding the small-conductance calcium-activated K+ channel (SK3) in lone atrial fibrillation patients. Atrial fibrillation (AF) is the most common cardiac arrhythmia. A genome-wide association study has recently associated an intronic single-nucleotide polymorphism (SNP) in KCNN3 with lone AF.

AB - The aim of this study was to screen KCNN3 encoding the small-conductance calcium-activated K+ channel (SK3) in lone atrial fibrillation patients. Atrial fibrillation (AF) is the most common cardiac arrhythmia. A genome-wide association study has recently associated an intronic single-nucleotide polymorphism (SNP) in KCNN3 with lone AF.

KW - Adult

KW - Age of Onset

KW - Atrial Fibrillation

KW - Case-Control Studies

KW - Cohort Studies

KW - Denmark

KW - Electrocardiography

KW - Exons

KW - Female

KW - Genetic Testing

KW - Genotype

KW - Humans

KW - Male

KW - Middle Aged

KW - Polymorphism, Single Nucleotide

KW - Small-Conductance Calcium-Activated Potassium Channels

UR - https://www.scopus.com/pages/publications/79959692889

U2 - 10.1093/europace/eur007

DO - 10.1093/europace/eur007

M3 - Journal article

C2 - 21398315

SN - 1099-5129

VL - 13

SP - 963

EP - 967

JO - Europace

JF - Europace

IS - 7

ER -

Screening of KCNN3 in patients with early-onset lone atrial fibrillation

Abstract

Keywords

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