Abstract
Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S. pneumoniae requires T>MIC above 40-50%. The second determinant for therapeutic activity is the ratio between maximum penicillin concentration in serum and MIC (Cmax/MIC). Considering penicillin pharmacokinetics, intravenous penicillin 2 million units four times a day is recommended as empirical treatment of CAP.
| Translated title of the contribution | Treatment of community-acquired pneumonia--treatment |
|---|---|
| Original language | Danish |
| Journal | Ugeskrift for Laeger |
| Volume | 170 |
| Issue number | 3 |
| Pages (from-to) | 127-30 |
| Number of pages | 4 |
| ISSN | 0041-5782 |
| Publication status | Published - 14 Jan 2008 |
| Externally published | Yes |
Keywords
- English Abstract
- Journal Article
- Review