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Saliva is inferior to nose and throat swabs for SARS-CoV-2 detection in children

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It is important to identify children and adolescents infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as they are often asymptomatic and may unintentionally spread the virus. However, information on the best sampling methods are limited. Most analyse nose and throat swabs with real-time polymerase chain reaction (RT-PCR), but these tests are uncomfortable and young children may not co-operate, increasing sub-optimal sample collection and false-negative results. Detecting SARS-CoV-2 in adult saliva, using RT-PCR1,2 has shown promise. However, young children struggle to produce saliva spontaneously and there have been conflicting results about using this method for children.3,4 In contrast, oral swabs cause minimal discomfort, do not generate aerosols, collect adequate viral material5 and can be used by parents or day care staff without personal protective equipment.

Original languageEnglish
Article number16049
JournalActa paediatrica
Volume110
Issue number12
Pages (from-to)3325-3326
Number of pages2
ISSN1651-2227
DOIs
Publication statusPublished - Dec 2021

    Research areas

  • COVID-19, Child, Humans, Nasopharynx, Pharynx, SARS-CoV-2, Saliva, Specimen Handling

ID: 66949740