Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel intestinal failure

Stephen J D O'Keefe; Palle B Jeppesen; Richard Gilroy; Marek Pertkiewicz; Johane P Allard; Bernard Messing

doi:10.1016/j.cgh.2012.12.029

Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel intestinal failure

Stephen J D O'Keefe, Palle B Jeppesen, Richard Gilroy, Marek Pertkiewicz, Johane P Allard, Bernard Messing

150 Citations (Scopus)

Abstract

Although home parenteral nutrition (PN) can save the lives of patients with massive bowel loss that results in short-bowel syndrome and intestinal failure, quality of life is impaired by PN and its complications. We examined the 12-month tolerability and efficacy of teduglutide to reduce PN dependency.

Original language	English
Journal	Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Volume	11
Issue number	7
Pages (from-to)	815-23.e1-3
ISSN	1542-3565
DOIs	https://doi.org/10.1016/j.cgh.2012.12.029
Publication status	Published - Jul 2013

Keywords

Adult
Aged
Aged, 80 and over
Double-Blind Method
Female
Gastrointestinal Agents
Humans
Male
Middle Aged
Parenteral Nutrition
Peptides
Short Bowel Syndrome
Treatment Outcome
Young Adult

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10.1016/j.cgh.2012.12.029

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O'Keefe, S. J. D., Jeppesen, P. B., Gilroy, R., Pertkiewicz, M., Allard, J. P., & Messing, B. (2013). Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel intestinal failure. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 11(7), 815-23.e1-3. https://doi.org/10.1016/j.cgh.2012.12.029

Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel intestinal failure. / O'Keefe, Stephen J D; Jeppesen, Palle B; Gilroy, Richard et al.
In: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, Vol. 11, No. 7, 07.2013, p. 815-23.e1-3.

Research output: Contribution to journal › Journal article › Research › peer-review

O'Keefe, SJD, Jeppesen, PB, Gilroy, R, Pertkiewicz, M, Allard, JP & Messing, B 2013, 'Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel intestinal failure', Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 11, no. 7, pp. 815-23.e1-3. https://doi.org/10.1016/j.cgh.2012.12.029

O'Keefe SJD, Jeppesen PB, Gilroy R, Pertkiewicz M, Allard JP, Messing B. Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel intestinal failure. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2013 Jul;11(7):815-23.e1-3. doi: 10.1016/j.cgh.2012.12.029

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Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel intestinal failure

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Keywords

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