Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials

F Keus; J Wetterslev; C Gluud; H G Gooszen; C J H M van Laarhoven

doi:10.1038/ajg.2008.22

Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials

F Keus, J Wetterslev, C Gluud, H G Gooszen, C J H M van Laarhoven

Copenhagen Trial Unit

78 Citations (Scopus)

Abstract

Meta-analysis of randomized trials with binary data can use a variety of statistical methods. Zero-event trials may create analytic problems. We explored how different methods may impact inferences from meta-analyses containing zero-event trials.

Original language	English
Journal	American Journal of Gastroenterology
Volume	104
Issue number	3
Pages (from-to)	546-51
Number of pages	6
ISSN	0002-9270
DOIs	https://doi.org/10.1038/ajg.2008.22
Publication status	Published - Mar 2009

Keywords

Bias (Epidemiology)
Data Interpretation, Statistical
Meta-Analysis as Topic
Randomized Controlled Trials as Topic

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10.1038/ajg.2008.22

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title = "Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials",

abstract = "Meta-analysis of randomized trials with binary data can use a variety of statistical methods. Zero-event trials may create analytic problems. We explored how different methods may impact inferences from meta-analyses containing zero-event trials.",

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KW - Meta-Analysis as Topic

KW - Randomized Controlled Trials as Topic

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Robustness assessments are needed to reduce bias in meta-analyses that include zero-event randomized trials

Abstract

Keywords

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