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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points: an international, multicenter, randomized, dose-finding, safety assessor-blinded, phase II trial

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  • Friedrich K Pühringer
  • Christopher Rex
  • Andreas W Sielenkämper
  • Casper Claudius
  • Per Bo Larsen
  • Martine E Prins
  • Matthias Eikermann
  • Karin S Khuenl-Brady
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Sugammadex (Org 25969), a novel, selective relaxant binding agent, was specifically designed to rapidly reverse rocuronium-induced neuromuscular blockade. The efficacy and safety of sugammadex for the reversal of profound, high-dose rocuronium-induced neuromuscular blockade was evaluated.
Original languageEnglish
JournalAnesthesiology News
Volume109
Issue number2
Pages (from-to)188-97
Number of pages10
ISSN0747-4679
DOIs
Publication statusPublished - 1 Aug 2008

    Research areas

  • Androstanols, Anesthesia, Intravenous, Anesthetics, Intravenous, Dose-Response Relationship, Drug, Drug Administration Schedule, Drug Toxicity, Female, Humans, Male, Middle Aged, Neuromuscular Blockade, Neuromuscular Depolarizing Agents, Propofol, gamma-Cyclodextrins

ID: 32797431