Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria

Vera A Essuman; Christine T Ntim-Amponsah; Birgitte S Astrup; George O Adjei; Jorgen A L Kurtzhals; Thomas A Ndanu; Bamenla Goka

doi:10.1186/1475-2875-9-232

Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria

Vera A Essuman, Christine T Ntim-Amponsah, Birgitte S Astrup, George O Adjei, Jorgen A L Kurtzhals, Thomas A Ndanu, Bamenla Goka

Department of Clinical Microbiology

37 Citations (Scopus)

Abstract

In malaria-endemic areas, reliably establishing parasitaemia for diagnosis of malaria can be difficult. A retinopathy with some features unique to severe malaria with a predictive value on prognosis, has been described. Detection of this retinopathy could be a useful diagnostic tool. This study was designed to determine the diagnostic usefulness of retinopathy on ophthalmoscopy in severe malaria syndromes: Cerebral malaria (CM) and non-cerebral severe malaria (non-CM), i.e. malaria with respiratory distress (RD) and malaria with severe anaemia (SA), in Ghanaian children. Secondly, to determine any association between retinopathy and the occurrence of convulsions in patients with CM.

Original language	English
Journal	Malaria Journal
Volume	9
Pages (from-to)	232
ISSN	1475-2875
DOIs	https://doi.org/10.1186/1475-2875-9-232
Publication status	Published - 1 Jan 2010

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title = "Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria",

abstract = "In malaria-endemic areas, reliably establishing parasitaemia for diagnosis of malaria can be difficult. A retinopathy with some features unique to severe malaria with a predictive value on prognosis, has been described. Detection of this retinopathy could be a useful diagnostic tool. This study was designed to determine the diagnostic usefulness of retinopathy on ophthalmoscopy in severe malaria syndromes: Cerebral malaria (CM) and non-cerebral severe malaria (non-CM), i.e. malaria with respiratory distress (RD) and malaria with severe anaemia (SA), in Ghanaian children. Secondly, to determine any association between retinopathy and the occurrence of convulsions in patients with CM.",

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T1 - Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria

AU - Essuman, Vera A

AU - Ntim-Amponsah, Christine T

AU - Astrup, Birgitte S

AU - Adjei, George O

AU - Kurtzhals, Jorgen A L

AU - Ndanu, Thomas A

AU - Goka, Bamenla

PY - 2010/1/1

Y1 - 2010/1/1

N2 - In malaria-endemic areas, reliably establishing parasitaemia for diagnosis of malaria can be difficult. A retinopathy with some features unique to severe malaria with a predictive value on prognosis, has been described. Detection of this retinopathy could be a useful diagnostic tool. This study was designed to determine the diagnostic usefulness of retinopathy on ophthalmoscopy in severe malaria syndromes: Cerebral malaria (CM) and non-cerebral severe malaria (non-CM), i.e. malaria with respiratory distress (RD) and malaria with severe anaemia (SA), in Ghanaian children. Secondly, to determine any association between retinopathy and the occurrence of convulsions in patients with CM.

AB - In malaria-endemic areas, reliably establishing parasitaemia for diagnosis of malaria can be difficult. A retinopathy with some features unique to severe malaria with a predictive value on prognosis, has been described. Detection of this retinopathy could be a useful diagnostic tool. This study was designed to determine the diagnostic usefulness of retinopathy on ophthalmoscopy in severe malaria syndromes: Cerebral malaria (CM) and non-cerebral severe malaria (non-CM), i.e. malaria with respiratory distress (RD) and malaria with severe anaemia (SA), in Ghanaian children. Secondly, to determine any association between retinopathy and the occurrence of convulsions in patients with CM.

UR - https://www.scopus.com/pages/publications/77955352495

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DO - 10.1186/1475-2875-9-232

M3 - Journal article

C2 - 20704742

SN - 1475-2875

VL - 9

SP - 232

JO - Malaria Journal

JF - Malaria Journal

ER -

Retinopathy in severe malaria in Ghanaian children--overlap between fundus changes in cerebral and non-cerebral malaria

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