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Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

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Harvard

Gliemann, L, Schmidt, JF, Olesen, J, Biensø, RS, Peronard, SL, Grandjean, SU, Mortensen, SP, Nyberg, M, Bangsbo, J, Pilegaard, H & Hellsten, Y 2013, 'Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men' The Journal of physiology, vol. 591, no. Pt 20, pp. 5047-59. https://doi.org/10.1113/jphysiol.2013.258061

APA

Gliemann, L., Schmidt, J. F., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., ... Hellsten, Y. (2013). Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men. The Journal of physiology, 591(Pt 20), 5047-59. https://doi.org/10.1113/jphysiol.2013.258061

CBE

MLA

Vancouver

Author

Gliemann, Lasse ; Schmidt, Jakob Friis ; Olesen, Jesper ; Biensø, Rasmus Sjørup ; Peronard, Sebastian Louis ; Grandjean, Simon Udsen ; Mortensen, Stefan Peter ; Nyberg, Michael ; Bangsbo, Jens ; Pilegaard, Henriette ; Hellsten, Ylva. / Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men. In: The Journal of physiology. 2013 ; Vol. 591, No. Pt 20. pp. 5047-59.

Bibtex

@article{f1140f1535b245b3bf6de26c9f713ab3,
title = "Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men",
abstract = "Ageing is thought to be associated with decreased vascular function partly due to oxidative stress. Resveratrol is a polyphenol, which in animal studies has been shown to decrease atherosclerosis, and improve cardiovascular health and physical capacity, in part through its effects on Sirtuin 1 signalling and through an improved antioxidant capacity. We tested the hypothesis that resveratrol supplementation enhances training-induced improvements in cardiovascular health parameters in aged men. Twenty-seven healthy physically inactive aged men (age: 65 ± 1 years; body mass index: 25.4 ± 0.7 kg m(-2); mean arterial pressure (MAP): 95.8 ± 2.2 mmHg; maximal oxygen uptake: 2488 ± 72 ml O2 min(-1)) were randomized into 8 weeks of either daily intake of either 250 mg trans-resveratrol (n = 14) or of placebo (n = 13) concomitant with high-intensity exercise training. Exercise training led to a 45{\%} greater (P",
author = "Lasse Gliemann and Schmidt, {Jakob Friis} and Jesper Olesen and Biens{\o}, {Rasmus Sj{\o}rup} and Peronard, {Sebastian Louis} and Grandjean, {Simon Udsen} and Mortensen, {Stefan Peter} and Michael Nyberg and Jens Bangsbo and Henriette Pilegaard and Ylva Hellsten",
year = "2013",
month = "10",
day = "15",
doi = "10.1113/jphysiol.2013.258061",
language = "English",
volume = "591",
pages = "5047--59",
journal = "The Journal of physiology",
issn = "0022-3751",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "Pt 20",

}

RIS

TY - JOUR

T1 - Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

AU - Gliemann, Lasse

AU - Schmidt, Jakob Friis

AU - Olesen, Jesper

AU - Biensø, Rasmus Sjørup

AU - Peronard, Sebastian Louis

AU - Grandjean, Simon Udsen

AU - Mortensen, Stefan Peter

AU - Nyberg, Michael

AU - Bangsbo, Jens

AU - Pilegaard, Henriette

AU - Hellsten, Ylva

PY - 2013/10/15

Y1 - 2013/10/15

N2 - Ageing is thought to be associated with decreased vascular function partly due to oxidative stress. Resveratrol is a polyphenol, which in animal studies has been shown to decrease atherosclerosis, and improve cardiovascular health and physical capacity, in part through its effects on Sirtuin 1 signalling and through an improved antioxidant capacity. We tested the hypothesis that resveratrol supplementation enhances training-induced improvements in cardiovascular health parameters in aged men. Twenty-seven healthy physically inactive aged men (age: 65 ± 1 years; body mass index: 25.4 ± 0.7 kg m(-2); mean arterial pressure (MAP): 95.8 ± 2.2 mmHg; maximal oxygen uptake: 2488 ± 72 ml O2 min(-1)) were randomized into 8 weeks of either daily intake of either 250 mg trans-resveratrol (n = 14) or of placebo (n = 13) concomitant with high-intensity exercise training. Exercise training led to a 45% greater (P

AB - Ageing is thought to be associated with decreased vascular function partly due to oxidative stress. Resveratrol is a polyphenol, which in animal studies has been shown to decrease atherosclerosis, and improve cardiovascular health and physical capacity, in part through its effects on Sirtuin 1 signalling and through an improved antioxidant capacity. We tested the hypothesis that resveratrol supplementation enhances training-induced improvements in cardiovascular health parameters in aged men. Twenty-seven healthy physically inactive aged men (age: 65 ± 1 years; body mass index: 25.4 ± 0.7 kg m(-2); mean arterial pressure (MAP): 95.8 ± 2.2 mmHg; maximal oxygen uptake: 2488 ± 72 ml O2 min(-1)) were randomized into 8 weeks of either daily intake of either 250 mg trans-resveratrol (n = 14) or of placebo (n = 13) concomitant with high-intensity exercise training. Exercise training led to a 45% greater (P

U2 - 10.1113/jphysiol.2013.258061

DO - 10.1113/jphysiol.2013.258061

M3 - Journal article

VL - 591

SP - 5047

EP - 5059

JO - The Journal of physiology

JF - The Journal of physiology

SN - 0022-3751

IS - Pt 20

ER -

ID: 43148425