TY - JOUR
T1 - Resting heart rate is a predictor of mortality in chronic obstructive pulmonary disease
AU - Jensen, Magnus Thorsten
AU - Marott, Jacob L
AU - Lange, Peter
AU - Vestbo, Jørgen
AU - Schnohr, Peter
AU - Nielsen, Olav Wendelboe
AU - Skov Jensen, Jan
AU - Jensen, Gorm B
PY - 2012
Y1 - 2012
N2 - The clinical significance of high heart rate in COPD is unexplored.We investigated the association between resting heart rate (RHR), pulmonary function, and prognosis in subjects with COPD.16,696 subjects above 40 years from The Copenhagen City Heart Study, a prospective study of the general population, followed for 35.3 years, 10,986 deaths occurring. Analyses were performed using time-dependent Cox-models and net reclassification index (NRI).RHR increased with severity of COPD (p85 bpm was 5.5 years in no COPD, 9.8 years in mild, 6.7 years in moderate, and 5.9 years in severe/very severe, (p
AB - The clinical significance of high heart rate in COPD is unexplored.We investigated the association between resting heart rate (RHR), pulmonary function, and prognosis in subjects with COPD.16,696 subjects above 40 years from The Copenhagen City Heart Study, a prospective study of the general population, followed for 35.3 years, 10,986 deaths occurring. Analyses were performed using time-dependent Cox-models and net reclassification index (NRI).RHR increased with severity of COPD (p85 bpm was 5.5 years in no COPD, 9.8 years in mild, 6.7 years in moderate, and 5.9 years in severe/very severe, (p
U2 - 10.1183/09031936.00072212
DO - 10.1183/09031936.00072212
M3 - Journal article
C2 - 23143550
SN - 0903-1936
JO - European Respiratory Journal
JF - European Respiratory Journal
ER -