Resolution of inflammation following treatment of ankylosing spondylitis is associated with new bone formation

Susanne J Pedersen; Praveena Chiowchanwisawakit; Robert G W Lambert; Mikkel Østergaard; Walter P Maksymowych

doi:10.3899/jrheum.100925

Resolution of inflammation following treatment of ankylosing spondylitis is associated with new bone formation

Susanne J Pedersen, Praveena Chiowchanwisawakit, Robert G W Lambert, Mikkel Østergaard, Walter P Maksymowych

86 Citations (Scopus)

Abstract

To test the hypothesis that in patients with ankylosing spondylitis (AS) a vertebral corner inflammatory lesion (CIL) visible on magnetic resonance imaging (MRI) that completely resolves following treatment with anti-tumor necrosis factor-α (TNF-α) agents is more likely to develop into a de novo syndesmophyte visible on a radiograph as compared to a vertebral corner with no CIL.

Original language	English
Journal	Journal of Rheumatology
Volume	38
Issue number	7
Pages (from-to)	1349-54
Number of pages	6
ISSN	0315-162X
DOIs	https://doi.org/10.3899/jrheum.100925
Publication status	Published - 2011

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title = "Resolution of inflammation following treatment of ankylosing spondylitis is associated with new bone formation",

abstract = "To test the hypothesis that in patients with ankylosing spondylitis (AS) a vertebral corner inflammatory lesion (CIL) visible on magnetic resonance imaging (MRI) that completely resolves following treatment with anti-tumor necrosis factor-α (TNF-α) agents is more likely to develop into a de novo syndesmophyte visible on a radiograph as compared to a vertebral corner with no CIL.",

author = "Pedersen, {Susanne J} and Praveena Chiowchanwisawakit and Lambert, {Robert G W} and Mikkel {\O}stergaard and Maksymowych, {Walter P}",

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language = "English",

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T1 - Resolution of inflammation following treatment of ankylosing spondylitis is associated with new bone formation

AU - Pedersen, Susanne J

AU - Chiowchanwisawakit, Praveena

AU - Lambert, Robert G W

AU - Østergaard, Mikkel

AU - Maksymowych, Walter P

PY - 2011

Y1 - 2011

N2 - To test the hypothesis that in patients with ankylosing spondylitis (AS) a vertebral corner inflammatory lesion (CIL) visible on magnetic resonance imaging (MRI) that completely resolves following treatment with anti-tumor necrosis factor-α (TNF-α) agents is more likely to develop into a de novo syndesmophyte visible on a radiograph as compared to a vertebral corner with no CIL.

AB - To test the hypothesis that in patients with ankylosing spondylitis (AS) a vertebral corner inflammatory lesion (CIL) visible on magnetic resonance imaging (MRI) that completely resolves following treatment with anti-tumor necrosis factor-α (TNF-α) agents is more likely to develop into a de novo syndesmophyte visible on a radiograph as compared to a vertebral corner with no CIL.

U2 - 10.3899/jrheum.100925

DO - 10.3899/jrheum.100925

M3 - Journal article

C2 - 21459937

VL - 38

SP - 1349

EP - 1354

JO - Journal of Rheumatology

JF - Journal of Rheumatology

SN - 0315-162X

IS - 7

ER -

Resolution of inflammation following treatment of ankylosing spondylitis is associated with new bone formation

Abstract

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