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Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

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Harvard

Wexler, DJ, Powe, CE, Barbour, LA, Buchanan, T, Coustan, DR, Corcoy, R, Damm, P, Dunne, F, Feig, DS, Ferrara, A, Harper, LM, Landon, MB, Meltzer, SJ, Metzger, BE, Roeder, H, Rowan, JA, Sacks, DA, Simmons, D, Umans, JG & Catalano, PM 2018, 'Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop', Obstetrics and Gynecology, vol. 132, no. 2, pp. 496-505. https://doi.org/10.1097/AOG.0000000000002726

APA

Wexler, D. J., Powe, C. E., Barbour, L. A., Buchanan, T., Coustan, D. R., Corcoy, R., Damm, P., Dunne, F., Feig, D. S., Ferrara, A., Harper, L. M., Landon, M. B., Meltzer, S. J., Metzger, B. E., Roeder, H., Rowan, J. A., Sacks, D. A., Simmons, D., Umans, J. G., & Catalano, P. M. (2018). Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Obstetrics and Gynecology, 132(2), 496-505. https://doi.org/10.1097/AOG.0000000000002726

CBE

Wexler DJ, Powe CE, Barbour LA, Buchanan T, Coustan DR, Corcoy R, Damm P, Dunne F, Feig DS, Ferrara A, Harper LM, Landon MB, Meltzer SJ, Metzger BE, Roeder H, Rowan JA, Sacks DA, Simmons D, Umans JG, Catalano PM. 2018. Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Obstetrics and Gynecology. 132(2):496-505. https://doi.org/10.1097/AOG.0000000000002726

MLA

Vancouver

Author

Wexler, Deborah J ; Powe, Camille E ; Barbour, Linda A ; Buchanan, Thomas ; Coustan, Donald R ; Corcoy, Rosa ; Damm, Peter ; Dunne, Fidelma ; Feig, Denice S ; Ferrara, Assiamira ; Harper, Lorie M ; Landon, Mark B ; Meltzer, Sara J ; Metzger, Boyd E ; Roeder, Hilary ; Rowan, Janet A ; Sacks, David A ; Simmons, David ; Umans, Jason G ; Catalano, Patrick M. / Research Gaps in Gestational Diabetes Mellitus : Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. In: Obstetrics and Gynecology. 2018 ; Vol. 132, No. 2. pp. 496-505.

Bibtex

@article{522a114444b64790a814ce1f55932a00,
title = "Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop",
abstract = "The National Institute of Diabetes and Digestive and Kidney Diseases convened a workshop on research gaps in gestational diabetes mellitus (GDM) with a focus on 1) early pregnancy diagnosis and treatment and 2) pharmacologic treatment strategies. This article summarizes the proceedings of the workshop. In early pregnancy, the appropriate diagnostic criteria for the diagnosis of GDM remain poorly defined, and an effect of early diagnosis and treatment on the risk of adverse outcomes has not been demonstrated. Despite many small randomized controlled trials of glucose-lowering medication treatment in GDM, our understanding of medication management of GDM is incomplete as evidenced by discrepancies among professional society treatment guidelines. The comparative effectiveness of insulin, metformin, and glyburide remains uncertain, particularly with respect to long-term outcomes. Additional topics in need of further research identified by workshop participants included phenotypic heterogeneity in GDM and novel and individualized treatment approaches. Further research on these topics is likely to improve our understanding of the pathophysiology and treatment of GDM to improve both short- and long-term outcomes for mothers and their children.",
author = "Wexler, {Deborah J} and Powe, {Camille E} and Barbour, {Linda A} and Thomas Buchanan and Coustan, {Donald R} and Rosa Corcoy and Peter Damm and Fidelma Dunne and Feig, {Denice S} and Assiamira Ferrara and Harper, {Lorie M} and Landon, {Mark B} and Meltzer, {Sara J} and Metzger, {Boyd E} and Hilary Roeder and Rowan, {Janet A} and Sacks, {David A} and David Simmons and Umans, {Jason G} and Catalano, {Patrick M}",
year = "2018",
month = aug,
doi = "10.1097/AOG.0000000000002726",
language = "English",
volume = "132",
pages = "496--505",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams & Wilkins",
number = "2",

}

RIS

TY - JOUR

T1 - Research Gaps in Gestational Diabetes Mellitus

T2 - Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

AU - Wexler, Deborah J

AU - Powe, Camille E

AU - Barbour, Linda A

AU - Buchanan, Thomas

AU - Coustan, Donald R

AU - Corcoy, Rosa

AU - Damm, Peter

AU - Dunne, Fidelma

AU - Feig, Denice S

AU - Ferrara, Assiamira

AU - Harper, Lorie M

AU - Landon, Mark B

AU - Meltzer, Sara J

AU - Metzger, Boyd E

AU - Roeder, Hilary

AU - Rowan, Janet A

AU - Sacks, David A

AU - Simmons, David

AU - Umans, Jason G

AU - Catalano, Patrick M

PY - 2018/8

Y1 - 2018/8

N2 - The National Institute of Diabetes and Digestive and Kidney Diseases convened a workshop on research gaps in gestational diabetes mellitus (GDM) with a focus on 1) early pregnancy diagnosis and treatment and 2) pharmacologic treatment strategies. This article summarizes the proceedings of the workshop. In early pregnancy, the appropriate diagnostic criteria for the diagnosis of GDM remain poorly defined, and an effect of early diagnosis and treatment on the risk of adverse outcomes has not been demonstrated. Despite many small randomized controlled trials of glucose-lowering medication treatment in GDM, our understanding of medication management of GDM is incomplete as evidenced by discrepancies among professional society treatment guidelines. The comparative effectiveness of insulin, metformin, and glyburide remains uncertain, particularly with respect to long-term outcomes. Additional topics in need of further research identified by workshop participants included phenotypic heterogeneity in GDM and novel and individualized treatment approaches. Further research on these topics is likely to improve our understanding of the pathophysiology and treatment of GDM to improve both short- and long-term outcomes for mothers and their children.

AB - The National Institute of Diabetes and Digestive and Kidney Diseases convened a workshop on research gaps in gestational diabetes mellitus (GDM) with a focus on 1) early pregnancy diagnosis and treatment and 2) pharmacologic treatment strategies. This article summarizes the proceedings of the workshop. In early pregnancy, the appropriate diagnostic criteria for the diagnosis of GDM remain poorly defined, and an effect of early diagnosis and treatment on the risk of adverse outcomes has not been demonstrated. Despite many small randomized controlled trials of glucose-lowering medication treatment in GDM, our understanding of medication management of GDM is incomplete as evidenced by discrepancies among professional society treatment guidelines. The comparative effectiveness of insulin, metformin, and glyburide remains uncertain, particularly with respect to long-term outcomes. Additional topics in need of further research identified by workshop participants included phenotypic heterogeneity in GDM and novel and individualized treatment approaches. Further research on these topics is likely to improve our understanding of the pathophysiology and treatment of GDM to improve both short- and long-term outcomes for mothers and their children.

U2 - 10.1097/AOG.0000000000002726

DO - 10.1097/AOG.0000000000002726

M3 - Journal article

C2 - 29995731

VL - 132

SP - 496

EP - 505

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 2

ER -

ID: 56321355