Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine

A L Esserlind, Anne Francke Christensen, H Le, M Kirchmann, A W Hauge, N M Toyserkani, Torben Lindskov Hansen, Niels Grarup, T Werge, S Steinberg, F Bettella, H Stefansson, Jes Olesen

65 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE: Genetic factors contribute to the aetiology of the prevalent form of migraine without aura (MO) and migraine with typical aura (MTA). Due to the complex inheritance of MO and MTA, the genetic background is still not fully established. In a population-based genome-wide association study by Chasman et al. (Nat Genet 2011: 43: 695-698), three common variants were found to confer risk of migraine at a genome-wide significant level (P 
Original languageEnglish
JournalEuropean Journal of Neurology
Pages (from-to)765-772
Number of pages8
ISSN1351-5101
DOIs
Publication statusPublished - May 2013

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