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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Renal lactate elimination is maintained during moderate exercise in humans

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  1. Performance changes during the off-season period in football players - Effects of age and previous hamstring injury

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  2. Differential time responses in inflammatory and oxidative stress markers after a marathon: An observational study

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  3. Effects of the Nordic Hamstring exercise on sprint capacity in male football players: a randomized controlled trial

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  1. Fibrogenesis and inflammation contribute to the pathogenesis of cirrhotic cardiomyopathy

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  2. Muscle-liver substrate fluxes in exercising humans and potential effects on hepatic metabolism

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  3. Measurement of peripheral arterial tonometry in patients with diabetic foot ulcers during courses of hyperbaric oxygen treatment

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Abstract Reduced hepatic lactate elimination initiates blood lactate accumulation during incremental exercise. In this study, we wished to determine whether renal lactate elimination contributes to the initiation of blood lactate accumulation. The renal arterial-to-venous (a-v) lactate difference was determined in nine men during sodium lactate infusion to enhance the evaluation (0.5 mol · L(-1) at 16 ± 1 mL · min(-1); mean ± s) both at rest and during cycling exercise (heart rate 139 ± 5 beats · min(-1)). The renal release of erythropoietin was used to detect kidney tissue ischaemia. At rest, the a-v O(2) (CaO(2)-CvO(2)) and lactate concentration differences were 0.8 ± 0.2 and 0.02 ± 0.02 mmol · L(-1), respectively. During exercise, arterial lactate and CaO(2)-CvO(2) increased to 7.1 ± 1.1 and 2.6 ± 0.8 mmol · L(-1), respectively (P 
Original languageEnglish
JournalJournal of Sports Sciences
Volume30
Issue number2
Pages (from-to)149-53
Number of pages5
ISSN0264-0414
DOIs
Publication statusPublished - 2012

ID: 33192393