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Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis

Anne-Lise Kamper, Arne Høj Nielsen, Niels Baekgaard, Svend Just

3 Citations (Scopus)

Abstract

Combined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes a case of acute renal graft dysfunction following the addition of an ARB to existing ACE inhibition. This unmasked an unknown iliac artery stenosis. The case indicates a possible important role of Ang II generated by non-ACE pathways in this situation.

Original languageEnglish
JournalJournal of the renin-angiotensin-aldosterone system : JRAAS
Volume3
Issue number2
Pages (from-to)135-7
Number of pages3
ISSN1470-3203
DOIs
Publication statusPublished - Jun 2002
Externally publishedYes

Keywords

  • Angiography
  • Angiotensin Receptor Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Arterial Occlusive Diseases
  • Constriction, Pathologic
  • Female
  • Humans
  • Hypertension
  • Iliac Artery
  • Kidney Transplantation
  • Middle Aged
  • Treatment Failure

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