Remote ischemic preconditioning reduces thrombus formation in the rat

Diana Mathilde Røpcke; Vibeke E. Hjortdal; Gete Eschen Toft; Morten Ølgaard Jegstrup Jensen; Steen Dalby Kristensen

doi:10.1111/j.1538-7836.2012.04914.x

Remote ischemic preconditioning reduces thrombus formation in the rat

Diana Mathilde Røpcke, Vibeke E. Hjortdal, Gete Eschen Toft, Morten Ølgaard Jegstrup Jensen, Steen Dalby Kristensen

26 Citations (Scopus)

Abstract

Ischemic preconditioning (IPC) is known to protect tissue from ischemia and has effect both locally[] and systemically[]. Remote IPC (RIPC) induced by limb ischemia provides systemic protection against prolonged ischemia in the target organ. RIPC has been reported to reduce infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary angioplasty[] and is currently evaluated in patients with ischemic stroke undergoing thrombolysis (NCT00975962). © 2012 International Society on Thrombosis and Haemostasis.

Original language	English
Journal	Journal of Thrombosis and Haemostasis
Volume	10
Issue number	11
Pages (from-to)	2405-2406
ISSN	1538-7933
DOIs	https://doi.org/10.1111/j.1538-7836.2012.04914.x
Publication status	Published - 2012
Externally published	Yes

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10.1111/j.1538-7836.2012.04914.x

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abstract = "Ischemic preconditioning (IPC) is known to protect tissue from ischemia and has effect both locally[] and systemically[]. Remote IPC (RIPC) induced by limb ischemia provides systemic protection against prolonged ischemia in the target organ. RIPC has been reported to reduce infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary angioplasty[] and is currently evaluated in patients with ischemic stroke undergoing thrombolysis (NCT00975962). {\textcopyright} 2012 International Society on Thrombosis and Haemostasis.",

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doi = "10.1111/j.1538-7836.2012.04914.x",

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AU - Røpcke, Diana Mathilde

AU - Hjortdal, Vibeke E.

AU - Toft, Gete Eschen

AU - Jensen, Morten Ølgaard Jegstrup

AU - Kristensen, Steen Dalby

PY - 2012

Y1 - 2012

N2 - Ischemic preconditioning (IPC) is known to protect tissue from ischemia and has effect both locally[] and systemically[]. Remote IPC (RIPC) induced by limb ischemia provides systemic protection against prolonged ischemia in the target organ. RIPC has been reported to reduce infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary angioplasty[] and is currently evaluated in patients with ischemic stroke undergoing thrombolysis (NCT00975962). © 2012 International Society on Thrombosis and Haemostasis.

AB - Ischemic preconditioning (IPC) is known to protect tissue from ischemia and has effect both locally[] and systemically[]. Remote IPC (RIPC) induced by limb ischemia provides systemic protection against prolonged ischemia in the target organ. RIPC has been reported to reduce infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary angioplasty[] and is currently evaluated in patients with ischemic stroke undergoing thrombolysis (NCT00975962). © 2012 International Society on Thrombosis and Haemostasis.

UR - https://www.scopus.com/pages/publications/84868092919

U2 - 10.1111/j.1538-7836.2012.04914.x

DO - 10.1111/j.1538-7836.2012.04914.x

M3 - Journal article

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JO - Journal of Thrombosis and Haemostasis

JF - Journal of Thrombosis and Haemostasis

IS - 11

ER -

Remote ischemic preconditioning reduces thrombus formation in the rat

Abstract

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